Observational studyArthritis & rheumatology (Hoboken, N.J.)2024
Strength Training Is Associated With Less Knee Osteoarthritis: Data From the Osteoarthritis Initiative.
Observational study in Arthritis & rheumatology (Hoboken, N.J.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.
- Optimizing resistance training for pain management in knee and hip osteoarthritis: a pairwise and dose-response meta-analysis.Frontiers in public health · 2025Pooled it
- Combined mode-kinetic chain exercise with and without core stability exercises on patients with knee osteoarthritis.BMC musculoskeletal disorders · 2026Trial
- Association Between Volleyball Participation and Knee Osteoarthritis in Community-Dwelling Adults: A Cross-Sectional Analysis of the Osteoarthritis Initiative.Healthcare (Basel, Switzerland) · 2026Article
- Physiological specificity of muscle-strengthening activity: a comparative analysis of associations with arthritis and cardiovascular disease prevalence in U.S. adults (NHIS 2024).Preventive medicine reports · 2026Article
- Gardening/yardwork over a lifetime is associated with less symptomatic knee osteoarthritis: data from the Osteoarthritis Initiative.Clinical rheumatology · 2026Article
- Relationship of strength training lifetime exposure with functional outcomes and mobility over 4 years: Data from the Osteoarthritis Initiative.Journal of sport and health science · 2025Article
- Biomechanical analysis of hip, knee, and ankle joint contact forces during squats in elite powerlifters.PloS one · 2025Article
- The Impact of Strength/Resistance Training on Related Outcomes of Patients with Knee Osteoarthritis: A Systematic Review and Meta-Analysis Study : Strength/Resistance Training in Knee Osteoarthritis.Galen medical journal · 2025Article
- Effects of platelet-rich plasma combined with isometric quadriceps contraction on cartilage in a rat model of knee osteoarthritis.Regenerative therapy · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 7 institutions in 1 country.
Funding
Abstract
objectiveWe aimed to evaluate the relationship of a history of strength training with symptomatic and structural outcomes of knee osteoarthritis (OA).
methodsThis study was a retrospective, cross-sectional study within the Osteoarthritis Initiative (OAI), a multicenter prospective longitudinal observational study. Data were collected at four OAI clinical sites: Memorial Hospital of Rhode Island, the Ohio State University, the University of Pittsburgh, and the University of Maryland/Johns Hopkins. The study included 2,607 participants with complete data on strength training, knee pain, and radiographic evidence of knee OA (male, 44.2%; mean ± SD age 64.3 ± 9.0 years; mean ± SD body mass index 28.5 ± 4.9 kg/m
resultsThe fully adjusted odds ratios (95% confidence interval) for frequent knee pain, ROA, and SOA among those who participated in strength training any time in their lives were 0.82 (0.68-0.97), 0.83 (0.70-0.99), and 0.77 (0.63-0.94), respectively. Findings were similar when looking at the specific age ranges.
conclusionStrength training is beneficial for future knee health, counteracting long-held assumptions that strength training has adverse effects.
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.