Evidence map›Paper›PMID 37869505›Full record

ArticleFrontiers in neuroscience2023

Tracking cell turnover in human brain using

Sebastian S Roeder, Elisa A Bonnin, Ting-Di Wu, Jean-Luc Guerquin-Kern, Samir Jabari, Sebastian Brandner, Ilker Y Eyüpoglu, Stephanie Gollwitzer, Hajo M Hamer, Stefan T Gerner and 14 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 8 institutions in 5 countries.

Sebastian S RoederDepartment of Neurology, University of Erlangen-Nuremberg, Erlangen, Germany.
Elisa A BonninDepartment of Neuro- and Sensory Physiology, University Medical Center Göttingen, Excellence Cluster Multiscale Bioimaging, Center for Biostructural Imaging of Neurodegeneration, Göttingen, Germany.
Ting-Di WuInstitut Curie, PSL University, Université Paris-Saclay, CNRS UAR2016, Inserm US-43, Multimodal Imaging Center, Paris, France.
Jean-Luc Guerquin-KernInstitut Curie, PSL University, Université Paris-Saclay, CNRS UAR2016, Inserm US-43, Multimodal Imaging Center, Paris, France.
Samir JabariDepartment of Neuropathology, University of Erlangen-Nuremberg, Erlangen, Germany.
Sebastian BrandnerDepartment of Neurosurgery, University of Erlangen-Nuremberg, Erlangen, Germany.
Ilker Y EyüpogluDepartment of Neurosurgery, University of Erlangen-Nuremberg, Erlangen, Germany.
Stephanie GollwitzerDepartment of Neurology, University of Erlangen-Nuremberg, Erlangen, Germany.
Hajo M HamerDepartment of Neurology, University of Erlangen-Nuremberg, Erlangen, Germany.
Stefan T GernerDepartment of Neurology, University of Erlangen-Nuremberg, Erlangen, Germany.
Thorsten R DoeppnerDepartment of Neurology, Justus Liebig University, Gießen, Germany.
Christoph RummelDepartment of Veterinary Physiology and Biochemistry, Justus Liebig University, Gießen, Germany.
Elisabet EnglundDepartment of Clinical Sciences, University of Lund, Lund, Sweden.
Ralph Heimke-BrinckPharmacy, University of Erlangen-Nuremberg, Erlangen, Germany.
Tobias BorstPharmacy, University of Erlangen-Nuremberg, Erlangen, Germany.
Christoph DanielDepartment of Nephropathology, Institute of Pathology, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, Germany.
Kerstin AmannDepartment of Nephropathology, Institute of Pathology, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, Germany.
Ursula Schlötzer-SchrehardtDepartment of Ophthalmology, University Hospital, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, Germany.
Anton B TonchevDepartment of Anatomy and Cell Biology and Stem Cell Biology Research Institute, Medical University Varna, Varna, Bulgaria.
Karl RoesslerDepartment of Neurosurgery, University of Erlangen-Nuremberg, Erlangen, Germany.
Stefan SchwabDepartment of Neurology, University of Erlangen-Nuremberg, Erlangen, Germany.
Olaf BergmannCenter for Regenerative Therapies, Technische Universität Dresden, Dresden, Germany.
Silvio O RizzoliDepartment of Neuro- and Sensory Physiology, University Medical Center Göttingen, Excellence Cluster Multiscale Bioimaging, Center for Biostructural Imaging of Neurodegeneration, Göttingen, Germany.
Hagen B HuttnerDepartment of Neurology, University of Erlangen-Nuremberg, Erlangen, Germany.
Friedrich-Alexander-Universität Erlangen-Nürnberg · DEUniversitätsmedizin Göttingen · DEUniversity of Giessen · DECentre National de la Recherche Scientifique · FRTU Dresden · DELund University · SEMedical University of Varna · BGUniversity of Vienna · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microcephaly is often caused by an impairment of the generation of neurons in the brain, a process referred to as neurogenesis. While most neurogenesis in mammals occurs during brain development, it thought to continue to take place through adulthood in selected regions of the mammalian brain, notably the hippocampus. However, the generality of neurogenesis in the adult brain has been controversial. While studies in mice and rats have provided compelling evidence for neurogenesis occurring in the adult rodent hippocampus, the lack of applicability in humans of key methods to demonstrate neurogenesis has led to an intense debate about the existence and, in particular, the magnitude of neurogenesis in the adult human brain. Here, we demonstrate the applicability of a powerful method to address this debate, that is, the

Indexed as

adultcell turnoverDNA-labelingglioblastomahippocampusNano-SIMSneurogenesis

Identifiers

PMID37869505
PMCPMC10585107
OpenAlexW4387366771

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.