Evidence map›Paper›PMID 37869400›Full record

ArticleCurrent therapeutic research, clinical and experimental2023

Potential Curative Effects of Aqueous Extracts of

Romeo Joel Guemmogne Temdie, Edwige Ymele Chiogo Vouffo, Borris Rosnay Tietcheu Galani, Bertrand Dabole Ladane, Josee Bianzoumbe, Marc Germain Kuum Minoue, Fidèle Ntchapda, Theophile Dimo

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Current therapeutic research, clinical and experimental, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Romeo Joel Guemmogne TemdieDepartment of Biological Sciences, Faculty of Science, University of Ngaoundéré, Ngaoundéré, Cameroon.
Edwige Ymele Chiogo VouffoFood and Drug Administration, Center for Drug Evaluation and Research, Office of New Drugs, Silver Spring, USA.
Borris Rosnay Tietcheu GalaniDepartment of Biological Sciences, Faculty of Science, University of Ngaoundéré, Ngaoundéré, Cameroon.
Bertrand Dabole LadaneDepartment of Biological Sciences, Faculty of Science, University of Ngaoundéré, Ngaoundéré, Cameroon.
Josee BianzoumbeDepartment of Biological Sciences, Faculty of Science, University of Ngaoundéré, Ngaoundéré, Cameroon.
Marc Germain Kuum MinoueDepartment of Psychology, Faculty of Letters and Human Social Sciences, University of Douala, Douala, Cameroon.
Fidèle NtchapdaDepartment of Biological Sciences, Faculty of Science, University of Ngaoundéré, Ngaoundéré, Cameroon.
Theophile DimoDepartment of Animal Biology and Physiology, Faculty of Science, University of Yaoundé I, Yaoundé, Cameroon.
University of Ngaoundéré · CMUnited States Food and Drug Administration · USUniversité de Yaoundé I · CMUniversity of Douala · CMUniversity of Maroua · CM

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Acetaminophen-induced liver injury remains a significant public health problem because available treatments are limited due to their adverse effects. Medicinal plants, which are an important source of bioactive molecules, could be an alternative treatment for liver disease. Objective: This study was designed to investigate the curative effect of aqueous extracts of Methods: Mice were divided into groups and treated with distilled water, silymarin (50 mg/kg), a reference hepatoprotective agent, and aqueous extracts of Results: Acetaminophen administration induced a significant ( Conclusions: The results obtained are evidence in favor of the development of a formulation based on the extracts of these plants against liver diseases.

Indexed as

AcetaminophenAnti-inflammatoryAntioxidantCissus quadrangularisJatropha gossypiifoliaLiver damage

Identifiers

PMID37869400
PMCPMC10587700
OpenAlexW4387213883

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.