Evidence map›Paper›PMID 37869338›Full record

ArticleQuantitative imaging in medicine and surgery2023

The effect of cartilage dehydration and rehydration on quantitative ultrashort echo time biomarkers.

Lidi Wan, Adam C Searleman, Yajun Ma, Jonathan H Wong, Judith Williams, Mark E Murphy, Jiang Du, Eric Y Chang, Guangyu Tang

Open access · diamondAbstract read
In one paragraph

Article in Quantitative imaging in medicine and surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 59% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Lidi WanDepartment of Radiology, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, China.
Adam C SearlemanDepartment of Radiology, University of California, San Diego, CA, USA.
Yajun MaDepartment of Radiology, University of California, San Diego, CA, USA.
Jonathan H WongRadiology Service, VA San Diego Healthcare System, San Diego, CA, USA.
Judith WilliamsRadiology Service, VA San Diego Healthcare System, San Diego, CA, USA.
Mark E MurphyOrthopaedic Surgery Service, VA San Diego Healthcare System, San Diego, CA, USA.
Jiang DuDepartment of Radiology, University of California, San Diego, CA, USA.
Eric Y ChangDepartment of Radiology, University of California, San Diego, CA, USA.
Guangyu TangDepartment of Radiology, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, China.
University of California San Diego · USVA San Diego Healthcare System · USTongji University · CN

Funding

Ultrashort Echo Time (UTE) Magnetic Resonance Imaging of BoneR01AR068987 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DU, JIANG · 2015 to 2024
$4.9M
Quantitative UTE MR Imaging: Sensitive Biomarkers for OsteoarthritisR01AR062581 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DU, JIANG · 2013 to 2022
$4.1M
Ultrashort Echo Time Magnetic Resonance Imaging of the Lumbar Intervertebral Disc.R01AR079484 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Yajun Ma · 2022 to 2026
$2.7M
Quantitative UTE MR Imaging of Myelin: Novel Biomarkers for Alzheimer's DiseaseRF1AG075717 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DU, JIANG · 2022 to 2022
$2.3M
Three-dimensional Ultrashort Echo Time Magnetic Resonance Imaging of EnthesesR01AR075825 · NIAMS · VETERANS MEDICAL RESEARCH FDN/SAN DIEGO · PI CHANG, ERIC Y · 2019 to 2023
$1.8M
Three-Dimensional UTE Magnetic Resonance Imaging of the Osteochondral JunctionR21AR075851 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MA, YAJUN · 2020 to 2021
$376k
Quantitative Measurement of Joint pH with Magnetic Resonance ImagingI01RX002604 · VA · VA SAN DIEGO HEALTHCARE SYSTEM · PI CHANG, ERIC Y · 2018 to 2022
–
Developing MRI Biomarkers of Myelin and Iron in Veterans with Traumatic Brain InjuryI01CX002211 · VA · VA SAN DIEGO HEALTHCARE SYSTEM · PI Jiang Du · 2021 to 2026
–
Quantitative Magnetic Resonance Imaging of Human Rotator Cuff TendonI01CX001388 · VA · VA SAN DIEGO HEALTHCARE SYSTEM · PI CHANG, ERIC Y · 2016 to 2024
–
CSRD VA I01 CX001388CSRD VA I01 CX002211NIAMS NIH HHS R01 AR062581NIAMS NIH HHS R01 AR068987NIAMS NIH HHS R01 AR075825NIAMS NIH HHS R01 AR079484NIAMS NIH HHS R21 AR075851NIA NIH HHS RF1 AG075717RRD VA I01 RX002604
6 · The paper itself

Abstract

Background: The effect of dehydration of Methods: A total of 37 cartilage samples were harvested from patients (n=5) who underwent total knee replacement. Fresh cartilage samples were exposed to air to dehydrate for 2 hours after baseline magnetic resonance (MR) scanning, then randomly divided into two groups: one soaking in native synovial fluid (n=17) and the other in normal saline (n=20) to rehydrate for 4 hours. UTE-based biomarkers [T Results: Dehydrating in air for 2 hours resulted in significant weight loss (P=0.000). T Conclusions: Cartilage dehydration resulted in significant changes in UTE biomarkers. Rehydrating with synovial fluid or normal saline had non-significant effect on all the evaluated UTE biomarkers except T

Indexed as

Cartilagedehydrationfreshrehydrationultrashort echo time magnetic resonance imaging (UTE-MRI)

Identifiers

PMID37869338
PMCPMC10585582
OpenAlexW4387023223

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.