Evidence map›Paper›PMID 37869257›Full record

ArticleFrontiers in science2023

The future of evolutionary medicine: sparking innovation in biomedicine and public health.

B Natterson-Horowitz, Athena Aktipis, Molly Fox, Peter D Gluckman, Felicia M Low, Ruth Mace, Andrew Read, Paul E Turner, Daniel T Blumstein

Abstract read
In one paragraph

Article in Frontiers in science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Harnessing Evolution and Biomimetics to Enhance Planetary Health: Kidney Insights.Journal of the American Society of Nephrology : JASN · 2025
    Review
  11. Article
  12. The gut and heart's role in reward processing.Frontiers in integrative neuroscience · 2025
    Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Placental-Heart Axis: An Evolutionary Perspective.International journal of molecular sciences · 2024
    Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

B Natterson-HorowitzDivision of Cardiology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, United States.ORCID 0000-0002-6145-9689
Athena AktipisDepartment of Psychology, Arizona State University, Tempe, AZ, United States.ORCID 0000-0002-7128-670X
Molly FoxDepartment of Anthropology, University of California, Los Angeles, Los Angeles, CA, United States.ORCID 0000-0001-9219-8971
Peter D GluckmanKoi Tū: The Centre for Informed Futures, University of Auckland, Auckland, New Zealand.ORCID 0000-0002-5711-1655
Felicia M LowKoi Tū: The Centre for Informed Futures, University of Auckland, Auckland, New Zealand.ORCID 0000-0001-7136-9997
Ruth MaceDepartment of Anthropology, University College London, London, United Kingdom.ORCID 0000-0002-6137-7739
Andrew ReadCenter for Infectious Disease Dynamics, Department of Biology, The Pennsylvania State University, State College, PA, United States.ORCID 0000-0001-7604-7903
Paul E TurnerDepartment of Ecology and Evolutionary Biology, Yale University, New Haven, CT, United States.ORCID 0000-0003-3490-7498
Daniel T BlumsteinDepartment of Ecology and Evolutionary Biology, University of California, Los Angeles, Los Angeles, CA, United States.ORCID 0000-0001-5793-9244

Funding

Effects of Acculturation on Gestational Biology in Mexican-American Pregnant WomenK01DK105110 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI FOX, MOLLY MAURER · 2015 to 2021
$782k
Social adversity, gestational stress physiology, and birth outcomes in Hispanic AmericansR03DK125524 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI FOX, MOLLY MAURER · 2020 to 2021
$234k
NIDDK NIH HHS K01 DK105110NIDDK NIH HHS R03 DK125524
6 · The paper itself

Abstract

Evolutionary medicine - i.e. the application of insights from evolution and ecology to biomedicine - has tremendous untapped potential to spark transformational innovation in biomedical research, clinical care and public health. Fundamentally, a systematic mapping across the full diversity of life is required to identify animal model systems for disease vulnerability, resistance, and counter-resistance that could lead to novel clinical treatments. Evolutionary dynamics should guide novel therapeutic approaches that target the development of treatment resistance in cancers (e.g.,

Indexed as

adaptationevolutionary medicineinnovationlife-historymismatchpublic healthresistancetrade-off

Identifiers

PMID37869257
PMCPMC10590274

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.