Evidence map›Paper›PMID 37868929›Full record

ArticleMovement disorders clinical practice2023

Exploring Asymmetric Fine Motor Impairment Trends in Early Parkinson's Disease via Keystroke Typing.

Ashley A Holmes, Michele Matarazzo, Ijah Mondesire-Crump, Emily Katz, Rahul Mahajan, Teresa Arroyo-Gallego

Open access · greenAbstract read
In one paragraph

Article in Movement disorders clinical practice, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Ashley A HolmesnQ Medical Cambridge Massachusetts USA.
Michele MatarazzoHM CINAC (Centro Integral de Neurociencias Abarca Campal), Fundación Hospitales de Madrid Hospital Universitario HM Puerta del Sur, HM Hospitales Madrid Spain.ORCID https://orcid.org/0000-0002-2907-8667
Ijah Mondesire-CrumpnQ Medical Cambridge Massachusetts USA.
Emily KatznQ Medical Cambridge Massachusetts USA.
Rahul MahajannQ Medical Cambridge Massachusetts USA.
Teresa Arroyo-GallegonQ Medical Cambridge Massachusetts USA.ORCID https://orcid.org/0000-0003-2874-0230
China Medical Board · USBrigham and Women's Hospital · USHM Hospitales · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The nQiMechPD algorithm transforms natural typing data into a numerical index that characterizes motor impairment in people with Parkinson's Disease (PwPD). Objectives: Use nQiMechPD to compare asymmetrical progression of PD-related impairment in dominant (D-PD) versus non-dominant side onset (ND-PD) de-novo patients. Methods: Keystroke data were collected from 53 right-handed participants (15 D-PD, 13 ND-PD, 25 controls). We apply linear mixed effects modeling to evaluate participants' right, left, and both hands nQiMechPD relative change by group. Results: The 6-month nQiMechPD trajectories of right (** Conclusions: Significant differences between D-PD and ND-PD groups were observed, likely driven by contrasting dominant hand trends. Our findings suggest disease onset side may influence motor impairment progression, medication response, and functional outcomes in PwPD.

Indexed as

asymmetrydisease progressionmotor controlParkinson's diseasetyping

Identifiers

PMID37868929
PMCPMC10585965
OpenAlexW4385810447

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.