Evidence map›Paper›PMID 37868706›Full record

ReviewChild neurology open

Moebius Syndrome: An Updated Review of Literature.

Syed Abdullah Monawwer, Sajjad Ali, Raahim Naeem, Syed Hasan Ali, Azkah Rabbani, Maria Khan, Saba Saleem Qazi, Syed Muhammad Ismail Shah, Sabeeh Khawar Farooqui

Open access · hybridAbstract readReview
In one paragraph

Review in Child neurology open. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Neural Orchestration of Mandibular Development.International dental journal · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. The Etiology of Moebius Syndrome-Making the Case for Animal Models.International journal of molecular sciences · 2025
    Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Syed Abdullah MonawwerDepartment of Internal Medicine, Ziauddin Medical University, Karachi, Pakistan.
Sajjad AliDepartment of Internal Medicine, Ziauddin Medical University, Karachi, Pakistan.ORCID https://orcid.org/0000-0002-8024-5942
Raahim NaeemDepartment of Internal Medicine, Dow Medical College, Dow University of Health Sciences, Karachi, Pakistan.
Syed Hasan AliDepartment of Internal Medicine, Dow Medical College, Dow University of Health Sciences, Karachi, Pakistan.
Azkah RabbaniDepartment of Internal Medicine, Dow Medical College, Dow University of Health Sciences, Karachi, Pakistan.
Maria KhanDepartment of Internal Medicine, Ziauddin Medical University, Karachi, Pakistan.
Saba Saleem QaziDepartment of Internal Medicine, Ziauddin Medical University, Karachi, Pakistan.
Syed Muhammad Ismail ShahDepartment of Internal Medicine, Ziauddin Medical University, Karachi, Pakistan.
Sabeeh Khawar FarooquiDepartment of Internal Medicine, Ziauddin Medical University, Karachi, Pakistan.
Ziauddin University · PKDow University of Health Sciences · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Moebius Syndrome, is a rare, non-progressive congenital neuropathological syndrome characterized primarily by the underdevelopment of the facial (CN VII) and abducens nerve (CN VI). Other features of Moebius Syndrome include facial nerve paresis, ophthalmoplegias, orthodontic deficiencies (including crowded dentition, swollen and hyperplastic gingiva, dental calculus, etc.), musculoskeletal abnormalities, and impaired mental function. Due to the rarity of the disorder, very few case studies have been reported in the literature. This article summarizes the significant features of the disease according to commonalities in reported cases, along with several newly recognized features cited in recent literature. We have explored the different diagnostic criteria and the newly recognized imaging modalities that may be used. Understandably, the condition detrimentally affects a patient's quality of life; thus, treatment measures have also been outlined. This study aims to provide updated literature on Moebius Syndrome MBS and improve understanding of the condition.

Indexed as

Abducens nerve paralysisFacial nerve paralysisMoebius syndromePoland syndrome

Identifiers

PMID37868706
PMCPMC10588417
OpenAlexW4387767603

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.