Evidence map›Paper›PMID 37868697›Full record

ArticleFrontiers in human neuroscience2023

Comparison of subthalamic unilateral and bilateral theta burst deep brain stimulation in Parkinson's disease.

Eileen Gülke, Martin A Horn, Julian Caffier, Hans Pinnschmidt, Wolfgang Hamel, Christian K E Moll, Alessandro Gulberti, Monika Pötter-Nerger

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in human neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Eileen GülkeDepartment of Neurology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Martin A HornDepartment of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Julian CaffierDepartment of Neurology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Hans PinnschmidtInstitute of Medical Biometry and Epidemiology, University Medical Center, Hamburg-Eppendorf, Hamburg, Germany.
Wolfgang HamelDepartment of Neurosurgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Christian K E MollInstitute of Neurophysiology and Pathophysiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Alessandro GulbertiDepartment of Neurology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Monika Pötter-NergerDepartment of Neurology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High-frequency, conventional deep brain stimulation (DBS) of the subthalamic nucleus (STN) in Parkinson's disease (PD) is usually applied bilaterally under the assumption of additive effects due to interhemispheric crosstalk. Theta burst stimulation (TBS-DBS) represents a new patterned stimulation mode with 5 Hz interburst and 200 Hz intraburst frequency, whose stimulation effects in a bilateral mode compared to unilateral are unknown. This single-center study evaluated acute motor effects of the most affected, contralateral body side in 17 PD patients with unilateral subthalamic TBS-DBS and 11 PD patients with bilateral TBS-DBS. Compared to therapy absence, both unilateral and bilateral TBS-DBS significantly improved (

Indexed as

bilateral stimulationdeep brain stimulationParkinson’s diseasesubthalamic nucleustheta burstunilateral stimulation

Identifiers

PMID37868697
PMCPMC10585145

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.