ReviewCureus2023
Insight Into Neonatal Sepsis: An Overview.
Review in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
54 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.
- Probiotics for preventing neonatal sepsis in preterm neonates: a systematic review and meta-analysis for clinical practice.Epidemiology and health · 2025Pooled it
- Trial
- Genomic characterization of CTX-M-15-producing Klebsiella pneumoniae ST709-KL9 from neonatal bacteraemia in eastern India.Molecular biology reports · 2026Article
- Impact of Early-Onset Sepsis on the Development and Severity of Intraventricular Hemorrhage in Premature Neonates: A Retrospective Single-Center Study.Children (Basel, Switzerland) · 2026Article
- Neonatal monocyte iron metabolism and immunometabolic responses in sepsis: a comparative ex vivo investigation.Pediatric research · 2026Article
- Diagnostic utility of neutrophil CD64 for early detection of neonatal sepsis in southwestern Nigeria: a comparative case-control study.BMC pediatrics · 2026Article
- Surveillance of bacterial colonization and infection in high-risk neonates admitted to tertiary referral hospital in Indonesia.BMC infectious diseases · 2026Article
- Sulodexide attenuates sepsis-induced lung injury in neonatal rats via TNF-α pathway.Pediatric research · 2026Article
- Burden, risk factors, and emerging microbiological trends of Gram-negative neonatal sepsis in Jordan: a retrospective cohort study.BMC infectious diseases · 2026Article
- Burden, clinical characteristics, and determinants of neonatal sepsis in a tertiary hospital in North-Central Nigeria: a retrospective study.BMC pediatrics · 2026Article
- Early-Onset Neonatal Sepsis: Clinical System Involvement and Maternal-Neonatal Risk Profiles in a Retrospective Cohort Study.Children (Basel, Switzerland) · 2026Article
- Article
- "Overview of Global Challenges in Dealing with Neonatal Sepsis and Responsibility of Healthcare Workers": A Narrative Review.Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine · 2026Review
- Bacteriological profile of early versus late-onset neonatal sepsis at tertiary care hospital in Nepal.BMC infectious diseases · 2026Article
- A Rare Case Report of Nosocomial Urosepsis due toCase reports in infectious diseases · 2026Article
- Retrospective Study of Pathogen Distribution and Antimicrobial Resistance in 283 Neonates with Bloodstream Infections at a Grade-A Tertiary Hospital in China, 2021-2024.Infection and drug resistance · 2026Article
- Rethinking neonatalFrontiers in immunology · 2026Article
- Therapeutic potential and translational challenges of extracellular vesicles in neonatal medicine.Bioengineering & translational medicine · 2026Review
- Diagnostic and prognostic utility of D-dimer and heparin-binding protein in neonatal sepsis: A prospective case-control study.World journal of clinical pediatrics · 2025Article
- Current state of microbiota clinical applications in neonatal and pediatric bacterial infections.Gut microbes · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 11 institutions in 7 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There are approximately 1.3 million cases of neonatal sepsis reported worldwide with deaths occurring more commonly in preterm and low-weight newborns. Neonatal sepsis is the third major cause of neonatal deaths resulting in 203,000 deaths per year. It is divided into two subtypes based on time of occurrence: early-onset neonatal sepsis (ENS), occurring within the first 72 hours of birth usually due to perinatal risk factors, and late-onset neonatal sepsis (LOS) usually occurring after the first week of life and up to 28th day of life. There are many complications associated with neonatal sepsis including septic shock, multiple organ failure, and death. It is vital for clinicians to know the signs and symptoms of neonatal sepsis in order to diagnose it early. Preventive measures, early diagnosis, appropriate antibiotic administration, timely supportive management, and the establishment of efficient management are vital in the prevention of severe complications or death. In this review, we aim to provide the most up-to-date information regarding risk factors, pathophysiology, signs and symptoms, diagnosis, and treatment of neonatal sepsis. We discuss the maternal and neonatal risk factors involved in the pathogenesis of neonatal sepsis and the signs and symptoms of early and late neonatal sepsis. We focus on the different pathogens involved and the markers used in the diagnosis and treatments available for each.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.