Evidence map›Paper›PMID 37868382›Full record

ArticleCureus2023

The Treatment of Insomnia Secondary to Generalized Anxiety Disorder: Evaluating Escitalopram Use With Concomitant High-Resolution, Relational, Resonance-Based, Electroencephalic Mirroring (HIRREM).

Kinan Sawar, Gautham Pavar, Nicole Xu, Amar Sawar

Abstract readCase Reports
In one paragraph

Article in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kinan SawarPlastic and Reconstructive Surgery, Wayne State University School of Medicine, Detroit, USA.
Gautham PavarAnesthesia, Wayne State University School of Medicine, Detroit, USA.
Nicole XuEmergency Medicine, Wayne State University School of Medicine, Detroit, USA.
Amar SawarNeurology, Southern Illinois University School of Medicine, Springfield, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patient autonomy is important. However, what if a patient seeks out poorly studied treatment options? In this case report, we describe a patient with insomnia secondary to generalized anxiety disorder (GAD) who was prescribed escitalopram but additionally used High-Resolution, Relational, Resonance-Based, Electroencephalic Mirroring (HIRREM) therapy. HIRREM is an electroencephalogram (EEG)-based therapy that has been evaluated for use in the treatment of various conditions including insomnia. However, there has only been one randomized clinical trial supporting the use of HIRREM for insomnia, and the Food and Drug Administration (FDA) has not approved HIRREM for insomnia. A few months after the patient initiated HIRREM therapy and escitalopram cessation, the patient's insomnia did not recur. We propose a case for how we approached educating a patient who was seeking out an alternative poorly tested therapy by helping him perform a cost-benefit analysis composed of treatment efficacy, cost, and side effects.

Indexed as

electroencephalogram (eeg)escitalopramgeneralized anxiety disorder (gad)health autonomyhirreminsomniainsomnia severity index

Identifiers

PMID37868382
PMCPMC10589415

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.