Evidence map›Paper›PMID 37867676›Full record

ArticleACS omega2023

Elucidating the Structure, Dynamics, and Interaction of a Choline Chloride and Citric Acid Based Eutectic System by Spectroscopic and Molecular Modeling Investigations.

Md Ackas Ali, Md Abdul Kaium, Sayed Nesar Uddin, Md Jaish Uddin, Oluseyi Olawuyi, Albert D Campbell, Carl Jacky Saint-Louis, Mohammad A Halim

Abstract read
In one paragraph

Article in ACS omega, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Md Ackas AliDepartment of Chemistry and Biochemistry, Kennesaw State University, Kennesaw, Georgia 30144, United States.
Md Abdul KaiumDivision of Quantum Chemistry, The Red-Green Research Center, BICCB, 16, Tejkunipara, Tejgaon, Dhaka 1215, Bangladesh.
Sayed Nesar UddinDivision of Quantum Chemistry, The Red-Green Research Center, BICCB, 16, Tejkunipara, Tejgaon, Dhaka 1215, Bangladesh.
Md Jaish UddinDivision of Quantum Chemistry, The Red-Green Research Center, BICCB, 16, Tejkunipara, Tejgaon, Dhaka 1215, Bangladesh.
Oluseyi OlawuyiDepartment of Chemistry and Biochemistry, Kennesaw State University, Kennesaw, Georgia 30144, United States.
Albert D CampbellDepartment of Chemistry and Biochemistry, Kennesaw State University, Kennesaw, Georgia 30144, United States.
Carl Jacky Saint-LouisDepartment of Chemistry and Biochemistry, Kennesaw State University, Kennesaw, Georgia 30144, United States.
Mohammad A HalimDepartment of Chemistry and Biochemistry, Kennesaw State University, Kennesaw, Georgia 30144, United States.ORCID https://orcid.org/0000-0002-1698-7044

Funding

Peach State Bridges to the DoctorateT32GM150548 · NIGMS · KENNESAW STATE UNIVERSITY · PI Kelly A Dyer, Melanie Christine Griffin · 2023 to 2026
$1.3M
NIGMS NIH HHS T32 GM150548
6 · The paper itself

Abstract

Eutectic solvent systems are versatile solvents that have found widespread use in numerous applications. Traditional solvents are homogeneous, having only one component, and their chemistry is relatively simple, with some exceptions. On the other hand, deep eutectic solvents (DESs) comprise binary components, generally a donor and an acceptor in hydrogen bonding with varying ratios. The interaction chemistry among the donor and acceptor involved in hydrogen bonding in DESs is complicated. Although numerous research is focused on the synthesis and application of DESs, few studies are reported to elucidate the complex structure and dynamic and interaction behavior of DESs. In this study, we employed calorimetry, vibrational spectroscopy techniques including FTIR and Raman, and nuclear magnetic resonance to derive insight into the structural feature and noncovalent contact of choline chloride (ChCl) and citric acid (CA) while they formed DESs. The 1:1 ChCl/CA eutectic system showed phase transitions and melting peaks with the most pronounced peak at 156.22 °C, suggesting the DESs melting at a lower temperature than the melting temperatures of ChCl and CA. In addition to IR and Raman findings,

Identifiers

PMID37867676
PMCPMC10586180

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.