Evidence map›Paper›PMID 37867050›Full record

ArticleZeitschrift fur medizinische Physik2025

Impact of the maximum ring difference on image quality and noise characteristics of a total-body PET/CT scanner.

Fabian P Schmidt, Julia G Mannheim, Pia M Linder, P Will, Lena Sophie Kiefer, Maurizio M Conti, Christian la Fougère, Ivo F Rausch

Abstract read
In one paragraph

Article in Zeitschrift fur medizinische Physik, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Large axial field of view PET/CT - Not just a longer PET gantry.Zeitschrift fur medizinische Physik · 2026
    Review
  2. Beyond image quality: Patient experience with long-axial field-of-view and standard PET/CT systems.European journal of nuclear medicine and molecular imaging · 2026
    Article
  3. Exploring extended [European journal of nuclear medicine and molecular imaging · 2026
    Article
  4. Article
  5. Article
  6. Whole-Body [Scientific data · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Low-activity [EJNMMI physics · 2025
    Article
  11. Article
  12. Article
  13. Image Quality and Quantitative PET Parameters of Low-Dose [Diagnostics (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Fabian P SchmidtDepartment of Nuclear Medicine and Clinical Molecular Imaging, University hospital Tuebingen, Tuebingen, Germany; Werner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, Eberhard-Karls University Tuebingen, Tuebingen, Germany. Electronic address: f.schmidt@med.uni-tuebingen.de.
Julia G MannheimWerner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, Eberhard-Karls University Tuebingen, Tuebingen, Germany; Cluster of Excellence iFIT (EXC 2180) "Image Guided and Functionally Instructed Tumor Therapies", University of Tuebingen, Tuebingen, Germany.
Pia M LinderDepartment of Nuclear Medicine and Clinical Molecular Imaging, University hospital Tuebingen, Tuebingen, Germany.
P WillDepartment of Nuclear Medicine and Clinical Molecular Imaging, University hospital Tuebingen, Tuebingen, Germany.
Lena Sophie KieferDepartment of Nuclear Medicine and Clinical Molecular Imaging, University hospital Tuebingen, Tuebingen, Germany.
Maurizio M ContiSiemens Medical Solutions USA Inc., Molecular Imaging, Knoxville, TN, USA.
Christian la FougèreDepartment of Nuclear Medicine and Clinical Molecular Imaging, University hospital Tuebingen, Tuebingen, Germany; Cluster of Excellence iFIT (EXC 2180) "Image Guided and Functionally Instructed Tumor Therapies", University of Tuebingen, Tuebingen, Germany.
Ivo F RauschQIMP Team, Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The sensitivity of a PET system highly depends on the axial acceptance angle or maximum ring difference (MRD), which can be particularly high for total-body scanners due to their larger axial field of views (aFOVs). This study aims to evaluate the impact on image quality (IQ) and noise performance when MRD85 (18°), the current standard for clinical use, is increased to MRD322 (52°) for the Biograph Vision Quadra (Siemens Healthineers).

methodsStudies with a cylindrical phantom covering the 106 cm aFOV and an IEC phantom filled with

resultsCV was improved by a factor of up to 1.49 and is highest for short acquisition times, peaks at the center field of view and mitigates parabolic in axial direction with no difference to MRD85 beyond the central 80 cm. No substantial differences between the two evaluated MRDs in regards to uniformity, SUV

conclusionPatient and phantom studies revealed that scan time could be lowered by approximately a factor of two with MRD322 while maintaining similar noise performance. The moderate degradation in spatial resolution for MRD322 is worth to exploit the full potential of the Quadra by either shorten scan times or leverage noise performance in particular for low count scenarios such as ultra-late imaging or dynamic studies with high temporal resolution.

Indexed as

Positron Emission Tomography Computed TomographyWhole Body ImagingEquipment DesignEquipment Failure AnalysisHumansPhantoms, ImagingReproducibility of ResultsSensitivity and SpecificitySignal-To-Noise RatioAcceptance angleBiograph Vision QuadraImage qualityLong field of viewTotal body PET

Identifiers

PMID37867050
PMCPMC12664500

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.