ReviewChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2024
Large aplasia cutis congenita of the vertex conservative management.
Review in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.
- Aplasia cutis congenita of the scalp with skull defect: an individual patient data systematic review of clinical features and treatment approaches.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026Pooled it
- Familial Aplasia Cutis Congenita With Exposure of the Meningeal Membrane: A Case Report.Cureus · 2026Article
- Aplasia Cutis Congenita in Bart's Syndrome: A Case Report and Literature Review.Clinical case reports · 2026Article
- A Case Report of Postoperative Cystic Hydrocephalus Following Duroplasty and Scalp Reconstruction in Neonatal With Aplasia Cutis Congenita and Extensive Craniodural Defect.Case reports in surgery · 2026Article
- Surgical management of aplasia cutis congenita of the scalp and skull defect in a resource-limited setting: A case report.Surgical neurology international · 2026Article
- Extensive Aplasia Cutis Congenita with Calvarial Defect and Superior Sagittal Sinus Exposure in a Term Neonate: A Case Report of Successful Healing with Conservative Management.International medical case reports journal · 2026Article
- Aplasia cutis congenita with unique vascular malformation and cranial hypoplasia: a case in a preterm infant.Clinical and experimental pediatrics · 2025Article
- An Extensive Case of Aplasia Cutis Congenita.Cureus · 2024Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAplasia cutis congenita (ACC) of the vertex with bone defect is a rare and begnin anomaly that can involve the epidermis, dermis, and subcutaneous tissues of the scalp with significant bone defect Bajpai and Pal (J Pediatr Surg 38(2):e4, 2003). When associated with skull defect, this rare malformation carries the risk of severe complications such as rupture of the superior sagittal sinus or infections. METHODS AND
resultsWe report a case of aplasia cutis congenita of the scalp with skull defect measuring 9 × 10 cm and an exposed sagittal sinus in a newborn. Both conservative and surgical methods have been proposed to treat this condition. In our case, conservative treatment was planned led to complete epithelization and the patient was healing well at 5 years of follow-up.
conclusionsACC of the vertex with a large scalp defects present a management dilemma Rocha et al. (Clin Case Rep 3(10):841-4, 2015). Based on a review of the literature, we report this case to demonstrate that even for the largest skin and bone defects, an initial conservative approach may allow for complete wound closure without the need for early surgical intervention.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.