Evidence map›Paper›PMID 37865778›Full record

ArticleBMC neurology2023

Prevalence and factors associated with pre-hospital delay among acute stroke patients at Mulago and Kiruddu national referral hospitals, Kampala: a cross-sectional study.

Keith Twirire Kakame, Jane Nakibuuka, Nelson Mukiza, Irene Andia-Biraro, Mark Kaddumukasa, Chris Burant, Elly Katabira, Martha Sajatovic

Open access · goldAbstract read
In one paragraph

Article in BMC neurology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
4.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Efficacy of five strategies to improve stroke action awareness in Spanish-speaking adults: A randomized comparison.International journal of stroke : official journal of the International Stroke Society · 2026
    Trial
  3. Article
  4. Article
  5. Article
  6. Prehospital stroke care in low- and middle-income countries: A World Stroke Organization (WSO) scientific statement.International journal of stroke : official journal of the International Stroke Society · 2025
    Review
  7. Time delays in emergency stroke care in a low-resource referral hospital in Ghana.African journal of emergency medicine : Revue africaine de la medecine d'urgence · 2025
    Article
  8. Article
  9. Article
  10. Delays in the Stroke Care Pathway in a Low-Income Setting: An Audit Study from Mozambique.International journal of environmental research and public health · 2025
    Observational
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
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  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Keith Twirire KakameDepartment of Medicine, College of Health Sciences, Makerere University, P.O Box 7072, Kampala, Uganda. keithkakame@gmail.com.
Jane NakibuukaMulago National Referral Hospital, P.O Box 7051, Kampala, Uganda.
Nelson MukizaRhineCynth Advisory Limited, Kampala, Uganda.
Irene Andia-BiraroDepartment of Medicine, College of Health Sciences, Makerere University, P.O Box 7072, Kampala, Uganda.
Mark KaddumukasaDepartment of Medicine, College of Health Sciences, Makerere University, P.O Box 7072, Kampala, Uganda.
Chris BurantFrances Payne Bolton School of Nursing, Case Western Reserve University, 10900 Euclid Ave, Cleveland, OH, TOMO, USA.
Elly KatabiraDepartment of Medicine, College of Health Sciences, Makerere University, P.O Box 7072, Kampala, Uganda.
Martha SajatovicNeurological and Behavioral Outcomes Center, University Hospitals Cleveland Medical Center & Case Western Reserve University School of Medicine, 11100 Euclid Avenue, Cleveland, OH, 44106, USA.
Makerere University · UGCase Western Reserve University · USMulago Hospital · UGUniversity Hospitals of Cleveland · US

Funding

A Targeted Self-Management Intervention for Reducing Stroke Risk Factors in High Risk UgandansR01NS118544 · NINDS · CASE WESTERN RESERVE UNIVERSITY · PI KATABIRA, ELLY T, SAJATOVIC, MARTHA X · 2020 to 2025
$3.0M
NINDS NIH HHS R01 NS118544
6 · The paper itself

Abstract

backgroundDespite advancements in acute stroke care, acute stroke patients present late for care resulting in high mortality and poor functional outcomes. This study determined the prevalence of pre-hospital delay and associated factors among adult acute stroke patients in Uganda.

methodsIn a hospital based, cross-sectional study, one hundred and forty-three study participants with confirmed acute stroke presenting to the emergency units of Mulago and Kiruddu national referral hospitals were enrolled. Using an interviewer-administered questionnaire, details on sociodemographics, onset of stroke, arrival at the tertiary facility, health system and clinical factors were collected. Descriptive statistics and modified Poisson regression analyses were performed to determine factors associated with prehospital delay.

resultsAmong the 143 study participants, nearly two-thirds (79/146) had ischemic stroke while a third (59/143) had haemorrhagic stroke. The mean age was 59 years (SD 16) and 51.7% of acute stroke patients were males. Ninety one percent (130/143) presented to the emergency unit after 3 hours. The majority (124/143) reported visiting lower-level facilities prior to referral to the tertiary facility. Staying outside Kampala district (PR: 1.28 (1.22-1.34), p < 0.001), and using hired or government ambulance for transport to tertiary facility (PR: 1.17 (1.13-1.20), p < 0.001) were associated with pre-hospital delay.

conclusionsPrevalence of pre-hospital delay among acute stroke patients presenting to public tertiary hospitals in Uganda is very high. The causes of pre hospital delay should be further explored qualitatively. Efforts to reduce prehospital delay should include improving pre-hospital transport systems for stroke patients.

Indexed as

StrokeAdultCross-Sectional StudiesFemaleHospitalsHumansMaleMiddle AgedPrevalenceReferral and ConsultationUgandaAcute stroke careLow and middle-income countriesPre-hospital delayStroke

Identifiers

PMID37865778
PMCPMC10589921
OpenAlexW4387847289

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.