Evidence map›Paper›PMID 37865737›Full record

ArticleBMC gastroenterology2023

The utility of self-expanding metal stents in benign biliary strictures- a retrospective case series.

Katlin Mallette, Jeffrey Hawel, Ahmad Elnahas, Nawar A Alkhamesi, Christopher M Schlachta, Ephraim S Tang

Open access · goldAbstract read
In one paragraph

Article in BMC gastroenterology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Katlin MalletteCSTAR (Canadian Surgical Technologies & Advanced Robotics), London Health Sciences Centre, and Department of Surgery, Western University, London, Canada.
Jeffrey HawelCSTAR (Canadian Surgical Technologies & Advanced Robotics), London Health Sciences Centre, and Department of Surgery, Western University, London, Canada.
Ahmad ElnahasCSTAR (Canadian Surgical Technologies & Advanced Robotics), London Health Sciences Centre, and Department of Surgery, Western University, London, Canada.
Nawar A AlkhamesiCSTAR (Canadian Surgical Technologies & Advanced Robotics), London Health Sciences Centre, and Department of Surgery, Western University, London, Canada.
Christopher M SchlachtaCSTAR (Canadian Surgical Technologies & Advanced Robotics), London Health Sciences Centre, and Department of Surgery, Western University, London, Canada.
Ephraim S TangDepartment of Surgery, Division of General Surgery, Schulich School of Medicine and Dentistry, Western University, University Hospital, London Health Sciences Centre, 339 Windermere Road, London, ON, N6A 5A5, Canada. Ephraim.Tang@lhsc.on.ca.
London Health Sciences Centre · CAWestern University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBenign biliary strictures can have a significant negative impact on patient quality of life. There are several modalities which can be utilized with the goal of stricture resolution. These techniques include balloon dilatation, placement of multiple plastic stents and more recently, the use of metal stents. The aim of this study was to evaluate the local success of self-expanding metal stents in successfully resolving benign biliary strictures.

methodsThis was a single institution, retrospective case series. Patients included in our study were patients who underwent endoscopic retrograde cholangiopancreatography with placement of self expanding metal stents for benign biliary strictures at our institution between 2016-2022. Patients were excluded for the following: malignant stricture, and inability to successfully place metal stent. Data was evaluated using two-sided t-test with 95% confidence interval.

resultsA total of 31 patients underwent placement of 43 self-expanding metal stents and met inclusion criteria. Mean age of patients was 59 ± 10 years, and were largely male (74.2% vs. 25.8%). Most strictures were anastomotic stricture post liver transplant (87.1%), while the remainder were secondary to chronic pancreatitis (12.9%). Complications of stent placement included cholangitis (18.6%), pancreatitis (2.3%), stent migration (20.9%), and inability to retrieve stent (4.7%). There was successful stricture resolution in 73.5% of patients with anastomotic stricture and 33.3% of patients with stricture secondary to pancreatitis. Resolution was more likely if stent duration was > / = 180 days (73.3% vs. 44.4%, p < 0.05). There was no demonstrated added benefit when stent duration was > / = 365 days (75% vs. 60.9%, p = 0.64).

conclusionsThis study demonstrates that self expanding metal stents are a safe and effective treatment for benign biliary strictures, with outcomes comparable to plastic stents with fewer interventions. This study indicates that the optimal duration to allow for stricture resolution is 180-365 days.

Indexed as

CholestasisPancreatitis, ChronicAgedCholangiopancreatography, Endoscopic RetrogradeConstriction, PathologicHumansMaleMetalsMiddle AgedQuality of LifeRetrospective StudiesStentsTreatment OutcomeMetalsBiliary strictureLiver transplantPlastic stentSelf expanding metal stents

Identifiers

PMID37865737
PMCPMC10589998
OpenAlexW4387846638

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.