Evidence map›Paper›PMID 37865401›Full record

Trial reportBMJ global health2023

Human-centred design bolsters vaccine confidence in the Philippines: results of a randomised controlled trial.

Mark Donald C Reñosa, Jonas Wachinger, Jerric Rhazel Guevarra, Jhoys Landicho-Guevarra, Mila F Aligato, Vivienne Endoma, Jeniffer Landicho, Thea Andrea Bravo, Carol Malacad, Maria Paz Demonteverde and 5 more

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMJ global health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 4 countries.

Mark Donald C ReñosaHeidelberg Institute of Global Health, Ruprecht-Karls-Universität Heidelberg, Heidelberg, Germany drmarkdonaldrn@gmail.com.ORCID 0000-0002-7414-7174
Jonas WachingerHeidelberg Institute of Global Health, Ruprecht-Karls-Universität Heidelberg, Heidelberg, Germany.ORCID 0000-0002-5480-3138
Jerric Rhazel GuevarraDepartment of Epidemiology and Biostatistics, Research Institute for Tropical Medicine - Department of Health, Muntinlupa City, Philippines.
Jhoys Landicho-GuevarraDepartment of Epidemiology and Biostatistics, Research Institute for Tropical Medicine - Department of Health, Muntinlupa City, Philippines.
Mila F AligatoDepartment of Epidemiology and Biostatistics, Research Institute for Tropical Medicine - Department of Health, Muntinlupa City, Philippines.
Vivienne EndomaDepartment of Epidemiology and Biostatistics, Research Institute for Tropical Medicine - Department of Health, Muntinlupa City, Philippines.ORCID 0000-0002-0225-3939
Jeniffer LandichoDepartment of Epidemiology and Biostatistics, Research Institute for Tropical Medicine - Department of Health, Muntinlupa City, Philippines.ORCID 0000-0002-4261-9296
Thea Andrea BravoDepartment of Epidemiology and Biostatistics, Research Institute for Tropical Medicine - Department of Health, Muntinlupa City, Philippines.
Carol MalacadDepartment of Epidemiology and Biostatistics, Research Institute for Tropical Medicine - Department of Health, Muntinlupa City, Philippines.
Maria Paz DemonteverdeDepartment of Epidemiology and Biostatistics, Research Institute for Tropical Medicine - Department of Health, Muntinlupa City, Philippines.
Catherine SilvestreDepartment of Epidemiology and Biostatistics, Research Institute for Tropical Medicine - Department of Health, Muntinlupa City, Philippines.
Kate BärnighausenHeidelberg Institute of Global Health, Ruprecht-Karls-Universität Heidelberg, Heidelberg, Germany.ORCID 0000-0002-4466-8921
Till BärnighausenHeidelberg Institute of Global Health, Ruprecht-Karls-Universität Heidelberg, Heidelberg, Germany.ORCID 0000-0002-4182-4212
Rachel P ChaseHeidelberg Institute of Global Health, Ruprecht-Karls-Universität Heidelberg, Heidelberg, Germany.ORCID 0000-0002-1503-4954
Shannon A McMahonHeidelberg Institute of Global Health, Ruprecht-Karls-Universität Heidelberg, Heidelberg, Germany.ORCID 0000-0002-8634-9283
Research Institute for Tropical Medicine · PHHeidelberg University · DEJohns Hopkins University · USUniversity of the Witwatersrand · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe public's confidence in vaccinations has eroded, and anti-vaccination movements have gained traction around the world, including in the Philippines. 'Salubong', a Filipino term, refers to welcoming someone back into one's life and elicits ideas about friendship and family relationships. We extended this concept to vaccines in efforts to design an intervention that would re-welcome vaccines into homes.

methodsUsing human-centred design, we developed and refined a story-based intervention that engages Filipino families, community leaders and community health workers. We conducted a randomised controlled trial among 719 caregivers of small children to test the developed intervention against a control video. We assessed the binary improvement (improvement vs no improvement) and the amount of improvement in vaccine attitudes and intentions after intervention exposure.

resultsAlthough the intervention group began with marginally higher baseline vaccine attitude scores, we found that 62% of the intervention group improved their vaccine attitude scores versus 37% of the control group (Fisher's exact, p<0.001). Among individuals whose scores improved after watching the assigned video, the intervention group saw higher mean attitude score improvements on the 5-point scale (Cohen's d=0.32 with 95% CI 0.10 to 0.54, two-sided t-test, p<0.01). We observed similar patterns among participants who stated that they had previously delayed or refused a vaccine for their child: 67% of 74 in the intervention group improved their vaccine attitude scores versus 42% of 54 in the control group (Fisher's exact, p<0.001). Among the subset of these individuals whose scores improved after watching the assigned video, the intervention group saw higher mean attitude score improvements on the 5-point scale that were marginally significant (Cohen's d=0.35 with 95% CI -0.01 to 0.70, two-sided t-test, p=0.06).

conclusionsOur results provide solid evidence for the potential of co-designed vaccine confidence campaigns and regulations.

Indexed as

VaccinesChildCommunity Health WorkersHumansPhilippinesVaccinationVaccineschild healthintervention studypublic healthvaccines

Identifiers

PMID37865401
PMCPMC10603469
OpenAlexW4387849980

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.