Evidence map›Paper›PMID 37864655›Full record

ArticleClinical journal of gastroenterology2024

A unique case of lymphoepithelioma-like HCC with osteoclast-like giant cells: CT imaging features with pathologic correlations.

Barbara Frittoli, Anna Castaldo, Marika Santarsiere, Raffaele Ascione, Giulia Tanzi, Andrea Ponsiglione, Gian Luca Baiocchi, Luigi Grazioli

Open access · hybridAbstract readCase Reports
In one paragraph

Article in Clinical journal of gastroenterology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Barbara FrittoliDepartment of Radiology, ASST Spedali Civili, Brescia, Italy.
Anna CastaldoDepartment of Advanced Biomedical Sciences, University of Naples Federico II, Via Pansini 5, 80131, Naples, Italy.
Marika SantarsiereDepartment of Advanced Biomedical Sciences, University of Naples Federico II, Via Pansini 5, 80131, Naples, Italy.
Raffaele AscioneDepartment of Advanced Biomedical Sciences, University of Naples Federico II, Via Pansini 5, 80131, Naples, Italy.
Giulia TanziDepartment of Pathology, ASST Cremona, Cremona, Italy.
Andrea PonsiglioneDepartment of Advanced Biomedical Sciences, University of Naples Federico II, Via Pansini 5, 80131, Naples, Italy. a.ponsiglionemd@gmail.com.ORCID http://orcid.org/0000-0002-0105-935X
Gian Luca BaiocchiDepartment of Clinical and Experimental Sciences, Surgical Clinic, University of Brescia, Brescia, Italy.
Luigi GrazioliDepartment of Radiology, ASST Spedali Civili, Brescia, Italy.
University of Naples Federico II · ITAzienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia · ITIstituti Ospitalieri di Cremona · ITFederico II University Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatocellular carcinoma (HCC) is the most common primary malignancy of the liver, with several histological variants being reported in literature. Hereby, we describe a case of a 77-year-old man with chronic liver disease referred to our department for performing a computed tomography (CT) due to a liver mass discovered at an abdominal ultrasound follow-up. At CT, a large, ill-defined lesion in the third hepatic segment was detected, characterized by progressive and delayed enhancement with minimal retraction of the hepatic capsule, associated with perihepatic adipose tissue inhomogeneity, mimicking a cholangiocarcinoma. At histopathological evaluation, the lesion turned out to be an HCC with lymphoepithelioma-like component and osteoclastic-like giant cells. This report focuses on the clinicopathological and radiological features of this unique case.

Indexed as

Bile Duct NeoplasmsCarcinoma, HepatocellularLiver NeoplasmsAgedBile Ducts, IntrahepaticGiant CellsHumansMaleOsteoclastsTomography, X-Ray ComputedComputed tomographyHepatocellular carcinoma (HCC)HistopathologyVariants

Identifiers

PMID37864655
PMCPMC10830663
OpenAlexW4387845961

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.