Evidence map›Paper›PMID 37864586›Full record

ArticleAnalytical and bioanalytical chemistry2023

LC-MS accurate quantification of a tryptic peptide co-eluted with an isobaric interference by using in-source collisional purification.

Alicia Maroto, Dany Jeanne Dit Fouque, Rémy Lartia, Antony Memboeuf

Abstract read
PubMed Publisher
In one paragraph

Article in Analytical and bioanalytical chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Alicia MarotoUniv Brest, CNRS, UMR 6521 CEMCA, F-29200, Brest, France.ORCID https://orcid.org/0000-0001-7821-7726
Dany Jeanne Dit FouqueUniv Brest, CNRS, UMR 6521 CEMCA, F-29200, Brest, France.ORCID https://orcid.org/0000-0001-6525-4632
Rémy LartiaUniv Grenoble-Alpes, CNRS, UMR 5250 DCM, F-38058, Grenoble, France.ORCID https://orcid.org/0000-0002-0049-6726
Antony MemboeufUniv Brest, CNRS, UMR 6521 CEMCA, F-29200, Brest, France. antony.memboeuf@univ-brest.fr.ORCID http://orcid.org/0000-0001-8540-2188

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Interferences from isobaric and isomeric compounds represent a common problem in liquid chromatography coupled to mass spectrometry (LC-MS). In this paper, in-source purification and chromatographic separation were combined with the aim of identifying isobaric contamination and quantifying accurately a compound despite the presence of an isobaric co-eluted interference. This is achieved by totally fragmenting in-source the precursor ions of the isobaric interference providing then LC-pseudo-MS

Indexed as

PeptidesTandem Mass SpectrometryCalibrationChromatography, LiquidReference StandardsPeptidesCo-elutionIn-source fragmentationInternal standard quantificationIsobaric interferenceLiquid chromatographyMass spectrometry

Identifiers

PMID37864586

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.