Evidence map›Paper›PMID 37864583›Full record

ArticleEating and weight disorders : EWD2023

Cognitive performance in hospitalized patients with severe or extreme anorexia nervosa.

Simone Daugaard Hemmingsen, Mia Beck Lichtenstein, Magnus Sjögren, Claire Gudex, Pia Veldt Larsen, René Klinkby Støving

Registry-linked trialOpen access · diamondAbstract read
In one paragraph

Article in Eating and weight disorders : EWD, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02502617 (Effect of Intensive Re-nutrition on Eating Disorder Psychopathology, Cognitive Functions, Anxiety, Depression, and Cortisol Level in Severe Anorexia Nervosa), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02502617 completednot on this map

Effect of Intensive Re-nutrition on Eating Disorder Psychopathology, Cognitive Functions, Anxiety, Depression, and Cortisol Level in Severe Anorexia Nervosa

TypeobservationalSponsorRené Klinkby StøvingRan2016 to 2023Enrolled36ConditionsAnorexia NervosaArmsmedical nutrition
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Simone Daugaard HemmingsenCentre for Eating Disorders, Odense University Hospital, Odense, Denmark. shemmingsen@health.sdu.dk.ORCID http://orcid.org/0000-0001-6789-7105
Mia Beck LichtensteinDepartment of Clinical Research, University of Southern Denmark, Odense, Denmark.ORCID http://orcid.org/0000-0002-7885-9187
Magnus SjögrenInstitute for Clinical Science, Department of Psychiatry, Umeå University, Umeå, Sweden.ORCID http://orcid.org/0000-0003-2060-1914
Claire GudexDepartment of Clinical Research, University of Southern Denmark, Odense, Denmark.ORCID http://orcid.org/0000-0003-3881-9890
Pia Veldt LarsenMental Health Services in the Region of Southern Denmark, Vejle, Denmark.ORCID http://orcid.org/0000-0002-8730-3703
René Klinkby StøvingCentre for Eating Disorders, Odense University Hospital, Odense, Denmark.ORCID http://orcid.org/0000-0002-4255-5544
University of Southern Denmark · DKMental Health Services · DKUmeå University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeSevere malnourishment may reduce cognitive performance in anorexia nervosa (AN). We studied cognitive functioning during intensive nutritional and medical stabilization in patients with severe or extreme AN and investigated associations between weight gain and cognitive improvement.

methodsA few days after admission to a specialized hospital unit, 33 patients with severe or extreme AN, aged 16-42 years, completed assessments of memory, cognitive flexibility, processing speed, and attention. Mean hospitalization was 6 weeks. Patients completed the same assessments at discharge (n = 22) following somatic stabilization and follow-up up to 6 months after discharge (n = 18).

resultsThe patients displayed normal cognitive performance at admission compared to normative data. During nutritional stabilization, body weight increased (mean: 11.3%; range 2.6-22.2%) and memory, attention, and processing speed improved (p values: ≤ 0.0002). No relationship between weight gain and cognitive improvement was observed at discharge or follow-up.

conclusionsCognitive performance at hospital admission was normal in patients with severe or extreme AN and improved during treatment although without association to weight gain. Based on these results, which are in line with previous studies, patients with severe or extreme AN need not be excluded from cognitively demanding tasks, possibly including psychotherapy. As patients may have other symptoms that interfere with psychotherapy, future research could investigate cognitive functioning in everyday life in patients with severe AN. TRIAL REGISTRATION NUMBER: The study is registered at clinicaltrials.gov (NCT02502617). LEVEL OF EVIDENCE: Level III, cohort study.

Indexed as

Anorexia NervosaBody WeightCognitionCohort StudiesHumansWeight GainAnorexia nervosaCognitive flexibilityEating disorderMalnutritionNeuropsychology

Identifiers

PMID37864583
PMCPMC10590307
OpenAlexW4387844287

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.