Evidence map›Paper›PMID 37864254›Full record

ArticleLaboratory animal research2023

Chemosensitivity to doxorubicin in primary cells derived from tumor of FVB/N-Trp53

Woobin Yun, Ji Eun Kim, You Jeong Jin, Yu Jeong Roh, Hee Jin Song, Ayun Seol, Tae Ryeol Kim, Kyeong Seon Min, Eun Seo Park, Gi Ho Park and 3 more

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Laboratory animal research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Methyl alcohol extract of marine green algaNutrition research and practice · 2025
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Woobin Yun *Department of Biomaterials Science (BK21 FOUR Program)/Life and Industry Convergence Research Institute, College of Natural Resources & Life Science, Pusan National University, Miryang, 50463, Korea.
Ji Eun Kim *Department of Biomaterials Science (BK21 FOUR Program)/Life and Industry Convergence Research Institute, College of Natural Resources & Life Science, Pusan National University, Miryang, 50463, Korea.
You Jeong JinDepartment of Biomaterials Science (BK21 FOUR Program)/Life and Industry Convergence Research Institute, College of Natural Resources & Life Science, Pusan National University, Miryang, 50463, Korea.
Yu Jeong RohDepartment of Biomaterials Science (BK21 FOUR Program)/Life and Industry Convergence Research Institute, College of Natural Resources & Life Science, Pusan National University, Miryang, 50463, Korea.
Hee Jin SongDepartment of Biomaterials Science (BK21 FOUR Program)/Life and Industry Convergence Research Institute, College of Natural Resources & Life Science, Pusan National University, Miryang, 50463, Korea.
Ayun SeolDepartment of Biomaterials Science (BK21 FOUR Program)/Life and Industry Convergence Research Institute, College of Natural Resources & Life Science, Pusan National University, Miryang, 50463, Korea.
Tae Ryeol KimDepartment of Biomaterials Science (BK21 FOUR Program)/Life and Industry Convergence Research Institute, College of Natural Resources & Life Science, Pusan National University, Miryang, 50463, Korea.
Kyeong Seon MinDepartment of Biomaterials Science (BK21 FOUR Program)/Life and Industry Convergence Research Institute, College of Natural Resources & Life Science, Pusan National University, Miryang, 50463, Korea.
Eun Seo ParkDepartment of Biomaterials Science (BK21 FOUR Program)/Life and Industry Convergence Research Institute, College of Natural Resources & Life Science, Pusan National University, Miryang, 50463, Korea.
Gi Ho ParkDepartment of Biomaterials Science (BK21 FOUR Program)/Life and Industry Convergence Research Institute, College of Natural Resources & Life Science, Pusan National University, Miryang, 50463, Korea.
Hyun Gu KangDepartment of Veterinary Theriogenology, College of Veterinary Medicine, Chungbuk National University, Cheongju, 28644, Korea.
Yeon Shik ChoiDepartment of Biomedical Analysis, Bio Campus of Korea Polytechnic, Nonsan, 32943, Korea.
Dae Youn HwangDepartment of Biomaterials Science (BK21 FOUR Program)/Life and Industry Convergence Research Institute, College of Natural Resources & Life Science, Pusan National University, Miryang, 50463, Korea. dyhwang@pusan.ac.kr.ORCID http://orcid.org/0000-0002-5144-1725
Pusan National University · KRChungbuk National University · KRKorea Bio Polytechnic College · KRYonsei University · KR

Funding

Ministry of Education F23YY8109033
6 · The paper itself

Abstract

backgroundTo evaluate the chemosensitivity to doxorubicin (DOX) in two primary cells derived from a tumor of FVB/N-Trp53

resultsThe primary tumor cells showed a significant (P < 0.05) defect for UV-induced upregulation of the Trp53 protein, and consisted of different ratios of leukocytes, fibroblasts, epithelial cells and mesenchymal cells. The IC

conclusionsTo the best of our knowledge, these results are the first to successfully detect an alteration in chemosensitivity to DOX in solid tumor cells and ascetic tumor cells derived from tumor of FVB/N-Trp53

Indexed as

Ascetic tumorChemosensitivityDoxorubicinG2 arrestSolid tumorTrp53

Identifiers

PMID37864254
PMCPMC10588074
OpenAlexW4387815706

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.