Evidence map›Paper›PMID 37864147›Full record

GuidelineBMC geriatrics2023

Tackling potentially inappropriate prescriptions in older adults: development of deprescribing criteria by consensus from experts in Colombia, Argentina, and Spain.

Roxana De Las Salas, Claudia Vaca-González, Javier Eslava-Schmalbach, Catalina Torres-Espinosa, Albert Figueras

Open access · goldAbstract readPractice GuidelineReview
In one paragraph

Guideline in BMC geriatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Roxana De Las SalasDepartment of Nursing, Km5 Via Puerto Colombia, Universidad del Norte, Barranquilla, Colombia. rdelassalas@uninorte.edu.co.
Claudia Vaca-GonzálezFaculty of Science, Department of Pharmacy, Universidad Nacional de Colombia, Carrera 45 N° 26-85, Bogota, Colombia.
Javier Eslava-SchmalbachFaculty of Medicine, Department of Surgery, Universidad Nacional de Colombia, Carrera 45 N° 26-85, Bogota, Colombia.
Catalina Torres-EspinosaFaculty of Medicine, Department of Internal Medicine, Universidad Nacional de Colombia, Carrera 45 N° 26-85, Bogota, Colombia.
Albert FiguerasFaculty of Medicine, Autonomus University of Barcelona, Bellaterra (Cerdanyola del Vallès), 08193, Barcelona, Spain.
Universidad Nacional de Colombia · COUniversidad del Norte · COUniversitat Autònoma de Barcelona · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPotentially inappropriate medication use is prevalent among older adults in primary care, leading to increased morbidity, adverse drug reactions, hospitalizations, and mortality. This study aimed to develop and validate a tool for identifying PIMs in older adults within the primary care setting. The tool is composed of a list of criteria and was created based on consensus among experts from three Spanish-speaking countries, including two from Latin America.

methodsA literature review was conducted to identify existing tools, and prescription patterns were evaluated in a cohort of 36,111 older adults. An electronic Delphi method, consisting of two rounds, was used to reach a formal expert consensus. The panel included 18 experts from Spain, Colombia, and Argentina. The content validity index, validity of each content item, and Kappa Fleiss statistical measure were used to establish reliability.

resultsRound one did not yield a consensus, but a definitive consensus was reached in round two. The resulting tool consisted of a list of 5 general recommendations per disease, along with 33 criteria related to potential problems, recommendations, and alternative therapeutic options. The overall content validity of the tool was 0.87, with a Kappa value of 0.69 (95% CI 0.64-0.73; Substantial).

conclusionsThe developed criteria provide a novel list that allows for a comprehensive approach to pharmacotherapy in older adults, intending to reduce inappropriate medication use, ineffective treatments, prophylactic therapies, and treatments with an unfavorable risk-benefit ratio for the given condition. Further studies are necessary to evaluate the impact of these criteria on health outcomes.

Indexed as

DeprescriptionsInappropriate PrescribingAgedArgentinaColombiaConsensusDrug PrescriptionsHumansPolypharmacyPotentially Inappropriate Medication ListReproducibility of ResultsSpainDeprescriptionsGeriatricsInappropriate PrescribingPolypharmacyPotentially inappropriate medication

Identifiers

PMID37864147
PMCPMC10588094
OpenAlexW4387820741

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.