Evidence map›Paper›PMID 37864140›Full record

ArticleBMC infectious diseases2023

Awareness of and willingness to use oral pre-exposure prophylaxis (PrEP) for HIV prevention among sexually active adults in Malawi: results from the 2020 Malawi population-based HIV impact assessment.

Alinune Nathanael Kabaghe, Victor Singano, Danielle Payne, Alice Maida, Rose Nyirenda, Kelsey Mirkovic, Andreas Jahn, Pragna Patel, Kristin Brown, Mansoor Farahani and 7 more

Open access · goldAbstract read
In one paragraph

Article in BMC infectious diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 5 institutions in 3 countries.

Alinune Nathanael KabagheDivision of Global HIV and TB, Centers for Disease Control and Prevention, Lilongwe, Malawi. qgo5@cdc.gov.
Victor SinganoDivision of Global HIV and TB, Centers for Disease Control and Prevention, Lilongwe, Malawi.
Danielle PayneDivision of Global HIV and TB, Centers for Disease Control and Prevention, Lilongwe, Malawi.
Alice MaidaDivision of Global HIV and TB, Centers for Disease Control and Prevention, Lilongwe, Malawi.
Rose NyirendaDepartment of HIV, AIDS and Hepatitis, Ministry of Health, Lilongwe, Malawi.
Kelsey MirkovicDivision of Global HIV and TB, Centers for Disease Control and Prevention, Lilongwe, Malawi.
Andreas JahnDepartment of HIV, AIDS and Hepatitis, Ministry of Health, Lilongwe, Malawi.
Pragna PatelDivision of Global HIV and TB, Centers for Disease Control and Prevention, Atlanta, United States of America.
Kristin BrownDivision of Global HIV and TB, Centers for Disease Control and Prevention, Atlanta, United States of America.
Mansoor FarahaniICAP Headquarters, Columbia University, New York, United States of America.
Felix KayigambaICAP in Malawi, Lilongwe, Malawi.
Lyson TenthaniICAP in Malawi, Lilongwe, Malawi.
Francis OgollahICAP in Malawi, Lilongwe, Malawi.
Andrew AuldDivision of Global HIV and TB, Centers for Disease Control and Prevention, Lilongwe, Malawi.
Fatima ZuluDivision of Global HIV and TB, Centers for Disease Control and Prevention, Lilongwe, Malawi.
Wezi MsungamaDivision of Global HIV and TB, Centers for Disease Control and Prevention, Lilongwe, Malawi.
Nellie Wadonda-KabondoDivision of Global HIV and TB, Centers for Disease Control and Prevention, Lilongwe, Malawi.
Christian Health Association of Malawi · MWCenters for Disease Control and Prevention · USMinistry of Health · MWCenters for Disease Control and Prevention · UGColumbia University · US

Funding

CDC HHS U2GGH002173
6 · The paper itself

Abstract

backgroundThe World Health Organization recommends Pre-Exposure Prophylaxis (PrEP) for all populations at substantial risk of HIV infection. Understanding PrEP awareness and interest is crucial for designing PrEP programs; however, data are lacking in sub-Saharan Africa. In Malawi, oral PrEP was introduced in 2018. We analyzed data from the 2020 Malawi Population-based HIV Impact Assessment (MPHIA) to assess PrEP awareness and factors associated with PrEP interest in Malawi.

methodsMPHIA 2020 was a national cross-sectional household-based survey targeting adults aged 15 + years. Oral PrEP was first described to the survey participants as taking a daily pill to reduce the chance of getting HIV. To assess awareness, participants were asked if they had ever heard of PrEP and to assess interest, were asked if they would take PrEP to prevent HIV, regardless of previous PrEP knowledge. Only sexually active HIV-negative participants are included in this analysis. We used multivariable logistic regression to assess sociodemographic factors and behaviors associated with PrEP interest. All results were weighted.

resultsWe included 13,995 HIV-negative sexually active participants; median age was 29 years old. Overall, 15.0%, 95% confidence interval (CI): 14.2-15.9% of participants were aware of PrEP. More males (adjusted odds ratio (aOR): 1.3, 95% CI: 1.2-1.5), those with secondary (aOR: 1.5, 95% CI: 1.2-2.0) or post-secondary (aOR: 3.4, 95% CI: 2.4-4.9) education and the wealthiest (aOR: 1.6, 95% CI: 1.2-2.0) were aware of PrEP than female, those without education and least wealthy participants, respectively. Overall, 73.0% (95% CI: 71.8-74.1%) of participants were willing to use PrEP. Being male (aOR: 1.2; 95% CI: 1.1-1.3) and having more than one sexual partner (aOR: 1.7 95% CI: 1.4-1.9), were associated higher willingness to use PrEP.

conclusionsIn this survey, prior PrEP knowledge and use were low while PrEP interest was high. High risk sexual behavior was associated with willingness to use PrEP. Strategies to increase PrEP awareness and universal access, may reduce HIV transmission.

Indexed as

HIV InfectionsPre-Exposure ProphylaxisAdultCross-Sectional StudiesFemaleHealth Knowledge, Attitudes, PracticeHIVHomosexuality, MaleHumansMalawiMaleHIVHIV preventionMalawiPopulation surveyPrEP

Identifiers

PMID37864140
PMCPMC10589952
OpenAlexW4387808895

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.