Evidence map›Paper›PMID 37864139›Full record

Trial reportBMC neurology2023

At-home computerized executive-function training to improve cognition and mobility in normal-hearing adults and older hearing aid users: a multi-centre, single-blinded randomized controlled trial.

Rachel Downey, Nathan Gagné, Niroshica Mohanathas, Jennifer L Campos, Kathleen M Pichora-Fuller, Louis Bherer, Maxime Lussier, Natalie A Phillips, Walter Wittich, Nancy St-Onge and 2 more

Registry-linked trialOpen access · goldAbstract readRandomized Controlled TrialMulticenter Study
In one paragraph

Trial report in BMC neurology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05418998 (Training Cognition to Improve Mobility and Listening in Older Adults with Hearing Loss), which is not on this map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05418998 nacompletednot on this map

Training Cognition to Improve Mobility and Listening in Older Adults with Hearing Loss: Moving from Lab to Life

TypeinterventionalSponsorConcordia University, MontrealRan2020 to 2024Enrolled63ConditionsAging, Age Related Hearing LossArmsExecutive function (EF) training
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 2 countries.

Rachel DowneyDepartment of Psychology, Concordia University, Montréal, Québec, Canada. Rachel.downey@mail.concordia.ca.
Nathan GagnéDepartment of Psychology, Concordia University, Montréal, Québec, Canada.
Niroshica MohanathasDepartment of Psychology, University of Toronto, Toronto, ON, Canada.
Jennifer L CamposDepartment of Psychology, University of Toronto, Toronto, ON, Canada.
Kathleen M Pichora-FullerDepartment of Psychology, University of Toronto, Toronto, ON, Canada.
Louis BhererDépartement de Médecine, Université de Montréal, Montréal, Québec, Canada.
Maxime LussierDépartement de Médecine, Université de Montréal, Montréal, Québec, Canada.
Natalie A PhillipsDepartment of Psychology, Concordia University, Montréal, Québec, Canada.
Walter WittichÉcole d'optométrie, Université de Montréal, Montréal, Québec, Canada.
Nancy St-OngePERFORM Centre, Concordia University, Montréal, Québec, Canada.
Jean-Pierre GagnéÉcole d'orthophonie Et d'audiologie, Université de Montréal, Montréal, Québec, Canada.
Karen LiDepartment of Psychology, Concordia University, Montréal, Québec, Canada.
Concordia University · CAMontreal Heart Institute · CAUniversité de Montréal · CAUniversity Health Network · CAConcordia University · USUniversity of Toronto · CA

Funding

CIHR PJT-166160
6 · The paper itself

Abstract

backgroundHearing loss predicts cognitive decline and falls risk. It has been argued that degraded hearing makes listening effortful, causing competition for higher-level cognitive resources needed for secondary cognitive or motor tasks. Therefore, executive function training has the potential to improve cognitive performance, in turn improving mobility, especially when older adults with hearing loss are engaged in effortful listening. Moreover, research using mobile neuroimaging and ecologically valid measures of cognition and mobility in this population is limited. The objective of this research is to examine the effect of at-home cognitive training on dual-task performance using laboratory and simulated real-world conditions in normal-hearing adults and older hearing aid users. We hypothesize that executive function training will lead to greater improvements in cognitive-motor dual-task performance compared to a wait-list control group. We also hypothesize that executive function training will lead to the largest dual-task improvements in older hearing aid users, followed by normal-hearing older adults, and then middle-aged adults.

methodsA multi-site (Concordia University and KITE-Toronto Rehabilitation Institute, University Health Network) single-blinded randomized controlled trial will be conducted whereby participants are randomized to either 12 weeks of at-home computerized executive function training or a wait-list control. Participants will consist of normal-hearing middle-aged adults (45-60 years old) and older adults (65-80 years old), as well as older hearing aid users (65-80 years old, ≥ 6 months hearing aid experience). Separate samples will undergo the same training protocol and the same pre- and post-evaluations of cognition, hearing, and mobility across sites. The primary dual-task outcome measures will involve either static balance (KITE site) or treadmill walking (Concordia site) with a secondary auditory-cognitive task. Dual-task performance will be assessed in an immersive virtual reality environment in KITE's StreetLab and brain activity will be measured using functional near infrared spectroscopy at Concordia's PERFORM Centre. DISCUSSION: This research will establish the efficacy of an at-home cognitive training program on complex auditory and motor functioning under laboratory and simulated real-world conditions. This will contribute to rehabilitation strategies in order to mitigate or prevent physical and cognitive decline in older adults with hearing loss.

trial registrationIdentifier: NCT05418998. https://clinicaltrials.gov/ct2/show/NCT05418998.

Indexed as

Hearing AidsHearing LossAgedAged, 80 and overCognitionExecutive FunctionExercise TherapyHearingHumansMiddle AgedAgingCognitive trainingDual-taskExecutive functionFallsHearing aidsHearing lossNeuroimagingPreventionVirtual reality

Identifiers

PMID37864139
PMCPMC10588173
OpenAlexW4387818152

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.