Evidence map›Paper›PMID 37864052›Full record

ArticleJournal of neural transmission (Vienna, Austria : 1996)2024

The role of immune and inflammatory-related indicators in cognitive dysfunction and disease severity in patients with parkinson's disease.

Xudong Zhao, Lei Li, Xiuping Ma, Yang Li, Beibei Gao, Weifeng Luo

Abstract read
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In one paragraph

Article in Journal of neural transmission (Vienna, Austria : 1996), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Review
  6. Differentiation and regulation of CD4Cellular and molecular life sciences : CMLS · 2024
    Review
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Xudong ZhaoDepartment of Neurology and Clinical Research Center of Neurological Disease, The Second Affiliated Hospital of Soochow University, Suzhou, 215004, Jiangsu Province, China.
Lei LiDepartment of General Medicine, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, 221000, Jiangsu Province, China.
Xiuping MaDepartment of Neurology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, 221000, Jiangsu Province, China.
Yang LiDepartment of Neurology, The Affiliated Huzhou Hospital, Zhejiang University School of Medicine (Huzhou Central Hospital), Huzhou, 313000, Zhejiang Province, China.
Beibei GaoDepartment of General Medicine, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, 221000, Jiangsu Province, China.
Weifeng LuoDepartment of Neurology and Clinical Research Center of Neurological Disease, The Second Affiliated Hospital of Soochow University, Suzhou, 215004, Jiangsu Province, China. luoweifeng999@126.com.
Xuzhou Medical College · CNSecond Affiliated Hospital of Soochow University · CNZhejiang University · CN

Funding

Suzhou Science and Technology Plan Project SS2019060the National Natural Science Foundation of China 81671270
6 · The paper itself

Abstract

We aimed to explore the role of immune and inflammatory indicators in cognitive dysfunction and disease severity in patients with Parkinson's disease (PD). A total of 123 patients with Parkinson's disease were enrolled in the PD group and 49 healthy volunteers in the control group. The patients with PD were further divided into 2 subgroups by evaluating cognitive function using the Montreal Cognitive Assessment (MoCA) and Mini-Mental State Examination (MMSE): the normal cognitive function (PD-NCI) group and the mild cognitive impairment (PD-MCI) group. Moreover, the PD patients were also divided into 2 subgroups using the defined scale of the Hoehn and Yahr (H-Y) stage: the early-stage group and the middle- and late-stage group. Immune and inflammatory indicators, including serum Aβ

Indexed as

Cognitive DysfunctionParkinson DiseaseHumansInterleukin-17Interleukin-6Patient AcuityTumor Necrosis Factor-alphaInterleukin-17Interleukin-6Tumor Necrosis Factor-alphaInflammatory cytokinesLymphocyte subpopulationMild cognitive impairmentParkinson’s disease

Identifiers

PMID37864052
OpenAlexW4387823812

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.