Evidence map›Paper›PMID 37864043›Full record

ArticleAnnals of biomedical engineering2024

Development of Novel Sutureless Balloon Expandable Fetal Heart Valve Device Using Absorbable Polycaprolactone Leaflets.

Sanchita S Bhat, Hieu T Bui, Anna Farnan, Katherine Vietmeyer, Aimee K Armstrong, Christopher K Breuer, Lakshmi Prasad Dasi

Abstract read
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Article in Annals of biomedical engineering, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sanchita S BhatWallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Office 232, 387 Technology Circle NW, Suite 200, Atlanta, GA, 30313-2412, USA.
Hieu T BuiWallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Office 232, 387 Technology Circle NW, Suite 200, Atlanta, GA, 30313-2412, USA.
Anna FarnanWallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Office 232, 387 Technology Circle NW, Suite 200, Atlanta, GA, 30313-2412, USA.
Katherine VietmeyerWallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Office 232, 387 Technology Circle NW, Suite 200, Atlanta, GA, 30313-2412, USA.
Aimee K ArmstrongThe Heart Center, Nationwide Children's Hospital, 700 Children's Dr., Columbus, OH, 43205, USA.
Christopher K BreuerDepartment of General Pediatric Surgery, Nationwide Children's Hospital, 700 Children's Dr., Columbus, OH, 43205, USA. christopher.breuer@nationwidechildrens.org.
Lakshmi Prasad DasiWallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Office 232, 387 Technology Circle NW, Suite 200, Atlanta, GA, 30313-2412, USA. lakshmi.dasi@gatech.edu.

Funding

Additional Ventures GR00006544
6 · The paper itself

Abstract

Congenital heart disease (CHD) accounts for nearly one-third of all congenital defects, and patients often require repeated heart valve replacements throughout their lives, due to failed surgical repairs and lack of durability of bioprosthetic valve implants. This objective of this study is to develop and in vitro test a fetal transcatheter pulmonary valve replacement (FTPVR) using sutureless techniques to attach leaflets, as an option to correct congenital defects such as pulmonary atresia with intact ventricular septum (PA/IVS), in utero. A balloon expandable design was analyzed using computational simulations to identify areas of failure. Five manufactured valves were assembled using the unique sutureless approach and tested in the fetal right heart simulator (FRHS) to evaluate hemodynamic characteristics. Computational simulations showed that the commissural loads on the leaflet material were significantly reduced by changing the attachment techniques. Hemodynamic analysis showed an effective orifice area of 0.08 cm

Indexed as

Heart Valve ProsthesisPolyestersPulmonary AtresiaTranscatheter Aortic Valve ReplacementAortic ValveFetal HeartHumansProsthesis DesignTreatment OutcomepolycaprolactonePolyestersBiomechanical analysisIn vitro testingMedical deviceNovel assembly techniqueResolvable metalResolvable polymerTissue engineered heart valveTranscatheter fetal valve replacement

Identifiers

PMID37864043

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.