Evidence map›Paper›PMID 37863961›Full record

ArticleScientific reports2023

Microvascular proliferation is associated with high tumour blood flow by mpMRI and disease progression in primary prostate cancer.

Astrid Børretzen, Lars A R Reisæter, Anders Ringheim, Karsten Gravdal, Svein A Haukaas, Kristine E Fasmer, Ingfrid H S Haldorsen, Christian Beisland, Lars A Akslen, Ole J Halvorsen

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Metabolic convergence of diabetes and prostate cancer: from dysglycemia to tumor microenvironment reprogramming.Mammalian genome : official journal of the International Mammalian Genome Society · 2026
    Review
  2. Imprinted high-Opto-electronic advances · 2026
    Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Astrid BørretzenCentre for Cancer Biomarkers CCBIO, Gade Laboratory for Pathology, Department of Clinical Medicine, University of Bergen, Bergen, Norway. astrid.borretzen@helse-bergen.no.
Lars A R ReisæterDepartment of Clinical Medicine, University of Bergen, Bergen, Norway.
Anders RingheimDepartment of Radiology, Haukeland University Hospital, Bergen, Norway.
Karsten GravdalDepartment of Pathology, Haukeland University Hospital, 5021, Bergen, Norway.
Svein A HaukaasDepartment of Urology, Haukeland University Hospital, Bergen, Norway.
Kristine E FasmerDepartment of Clinical Medicine, University of Bergen, Bergen, Norway.
Ingfrid H S HaldorsenDepartment of Clinical Medicine, University of Bergen, Bergen, Norway.
Christian BeislandDepartment of Clinical Medicine, University of Bergen, Bergen, Norway.
Lars A AkslenCentre for Cancer Biomarkers CCBIO, Gade Laboratory for Pathology, Department of Clinical Medicine, University of Bergen, Bergen, Norway.
Ole J HalvorsenCentre for Cancer Biomarkers CCBIO, Gade Laboratory for Pathology, Department of Clinical Medicine, University of Bergen, Bergen, Norway.
Haukeland University Hospital · NOUniversity of Bergen · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Active angiogenesis may be assessed by immunohistochemistry using Nestin, a marker of newly formed vessels, combined with Ki67 for proliferating cells. Here, we studied microvascular proliferation by Nestin-Ki67 co-expression in prostate cancer, focusing on relations to quantitative imaging parameters from anatomically matched areas obtained by preoperative mpMRI, clinico-pathological features and prognosis. Tumour slides from 67 patients (radical prostatectomies) were stained for Nestin-Ki67. Proliferative microvessel density (pMVD) and presence of glomeruloid microvascular proliferation (GMP) were recorded. From mpMRI, forward volume transfer constant (K

Indexed as

Multiparametric Magnetic Resonance ImagingProstatic NeoplasmsCell ProliferationDisease ProgressionHumansKi-67 AntigenMagnetic Resonance ImagingMaleNestinKi-67 AntigenNestin

Identifiers

PMID37863961
PMCPMC10589248
OpenAlexW4387812348

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.