Evidence map›Paper›PMID 37863897›Full record

ArticleCell death discovery2023

YAP nuclear translocation induced by HIF-1α prevents DNA damage under hypoxic conditions.

Heng-Ai Chang, Rui-Zhi Ou Yang, Jing-Ming Su, Thi My Hang Nguyen, Junne-Ming Sung, Ming-Jer Tang, Wen-Tai Chiu

Open access · goldAbstract read
In one paragraph

Article in Cell death discovery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 25 citations in OpenAlex.

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  14. Targeting Neuraminidase 4 Attenuates Kidney Fibrosis in Mice.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  15. Review
  16. Article
  17. Acute hypoxia stress mediatesFrontiers in immunology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Heng-Ai ChangInstitute of Basic Medical Sciences, National Cheng Kung University, Tainan, 701, Taiwan, ROC.ORCID http://orcid.org/0000-0001-7337-6728
Rui-Zhi Ou YangDepartment of Biomedical Engineering, National Cheng Kung University, Tainan, 701, Taiwan, ROC.
Jing-Ming SuDepartment of Biomedical Engineering, National Cheng Kung University, Tainan, 701, Taiwan, ROC.
Thi My Hang NguyenDepartment of Biomedical Engineering, National Cheng Kung University, Tainan, 701, Taiwan, ROC.
Junne-Ming SungDepartment of Internal Medicine, National Cheng Kung University Hospital, Tainan, 701, Taiwan, ROC.
Ming-Jer TangDepartment of Physiology, College of Medicine, National Cheng Kung University, Tainan, 701, Taiwan, ROC.
Wen-Tai ChiuInstitute of Basic Medical Sciences, National Cheng Kung University, Tainan, 701, Taiwan, ROC. wtchiu@mail.ncku.edu.tw.ORCID http://orcid.org/0000-0003-0310-0675
National Cheng Kung University · TWNational Cheng Kung University Hospital · TW

Funding

Ministry of Science and Technology, Taiwan (Ministry of Science and Technology of Taiwan) NSTC 112-2321-B-003-001Ministry of Science and Technology, Taiwan (Ministry of Science and Technology of Taiwan) NSTC 112-2740-B-006-002
6 · The paper itself

Abstract

Maladaptive repair of acute kidney injury (AKI) is associated with a high risk of developing chronic kidney disease deemed irremediable even in present days. When AKI arises from ischemia-reperfusion injury, hypoxia usually plays a major role. Although both hypoxia-inducible factor-1α (HIF-1α) and yes-associated protein (YAP) have been proven to promote renal cell survival under hypoxia, there is a lack of research that studies the crosstalk of the two and its effect on kidney repair. In studying the crosstalk, CoCl

Identifiers

PMID37863897
PMCPMC10589224
OpenAlexW4387808870

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.