Evidence map›Paper›PMID 37863877›Full record

ArticleScientific reports2023

Excitatory stimulation of the ventromedial prefrontal cortex reduces cognitive gambling biases via improved feedback learning.

Thomas Kroker, Miroslaw Wyczesany, Maimu Alissa Rehbein, Kati Roesmann, Ida Wessing, Anja Wiegand, Jens Bölte, Markus Junghöfer

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Thomas KrokerInstitute for Biomagnetism and Biosignalanalysis, University of Muenster, Malmedyweg 15, 48149, Muenster, Germany.
Miroslaw WyczesanyInstitute of Psychology, Jagiellonian University, Krakow, Poland.
Maimu Alissa RehbeinInstitute for Biomagnetism and Biosignalanalysis, University of Muenster, Malmedyweg 15, 48149, Muenster, Germany.
Kati RoesmannInstitute for Biomagnetism and Biosignalanalysis, University of Muenster, Malmedyweg 15, 48149, Muenster, Germany.
Ida WessingInstitute for Biomagnetism and Biosignalanalysis, University of Muenster, Malmedyweg 15, 48149, Muenster, Germany.
Anja WiegandInstitute for Biomagnetism and Biosignalanalysis, University of Muenster, Malmedyweg 15, 48149, Muenster, Germany.
Jens BölteOtto Creutzfeldt Center for Cognitive and Behavioral Neuroscience, University of Muenster, Muenster, Germany.
Markus JunghöferInstitute for Biomagnetism and Biosignalanalysis, University of Muenster, Malmedyweg 15, 48149, Muenster, Germany. markus.junghoefer@uni-muenster.de.
Center for Behavioral Brain Sciences · DEInstitute of Psychology · PLUniversity Hospital Münster · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Humans are subject to a variety of cognitive biases, such as the framing-effect or the gambler's fallacy, that lead to decisions unfitting of a purely rational agent. Previous studies have shown that the ventromedial prefrontal cortex (vmPFC) plays a key role in making rational decisions and that stronger vmPFC activity is associated with attenuated cognitive biases. Accordingly, dysfunctions of the vmPFC are associated with impulsive decisions and pathological gambling. By applying a gambling paradigm in a between-subjects design with 33 healthy adults, we demonstrate that vmPFC excitation via transcranial direct current stimulation (tDCS) reduces the framing-effect and the gambler's fallacy compared to sham stimulation. Corresponding magnetoencephalographic data suggest improved inhibition of maladaptive options after excitatory vmPFC-tDCS. Our analyses suggest that the underlying mechanism might be improved reinforcement learning, as effects only emerge over time. These findings encourage further investigations of whether excitatory vmPFC-tDCS has clinical utility in treating pathological gambling or other behavioral addictions.

Indexed as

GamblingTranscranial Direct Current StimulationAdultBiasCognitionFeedbackHumansPrefrontal Cortex

Identifiers

PMID37863877
PMCPMC10589243
OpenAlexW4387804489

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.