Evidence map›Paper›PMID 37863778›Full record

ArticleAcademic radiology2024

Technical Success and Reliability of Magnetic Resonance Elastography in Patients with Hepatic Iron Overload.

Jingjing Liu, Mengyue Huang, Yong Zhang, Feifei Yao, Xiaopan Zhang, Meng Yin, Kaiyu Wang, Jingliang Cheng

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PubMed Full text at PMC Publisher
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Article in Academic radiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Jingjing LiuDepartment of MR Imaging, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China (J.L., M.H., Y.Z., F.Y., X.Z., J.C.). Electronic address: liujingjing198631@126.com.
Mengyue HuangDepartment of MR Imaging, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China (J.L., M.H., Y.Z., F.Y., X.Z., J.C.).
Yong ZhangDepartment of MR Imaging, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China (J.L., M.H., Y.Z., F.Y., X.Z., J.C.).
Feifei YaoDepartment of MR Imaging, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China (J.L., M.H., Y.Z., F.Y., X.Z., J.C.).
Xiaopan ZhangDepartment of MR Imaging, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China (J.L., M.H., Y.Z., F.Y., X.Z., J.C.).
Meng YinDepartment of Radiology, Mayo Clinic, Rochester, Minnesota (M.Y.).
Kaiyu WangMR Research China, GE Healthcare, Beijing, PR China (K.W.).
Jingliang ChengDepartment of MR Imaging, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China (J.L., M.H., Y.Z., F.Y., X.Z., J.C.).

Funding

Comprehensive noninvasive assessment of liver histopathology in nonalcoholic fatty liver disease (NAFLD) via magnetic resonance imaging, cytometry and elastography (MR-ICE)R01EB017197 · NIBIB · MAYO CLINIC ROCHESTER · PI YIN, MENG · 2014 to 2025
$4.3M
Magnetic Resonance ElastographyR37EB001981 · NIBIB · MAYO CLINIC ROCHESTER · PI EHMAN, RICHARD L. · 2016 to 2025
$4.0M
Magnetic Resonance ElastographyR01EB001981 · NIBIB · MAYO CLINIC ROCHESTER · PI EHMAN, RICHARD L. · 2003 to 2013
$3.1M
NIBIB NIH HHS R01 EB001981NIBIB NIH HHS R01 EB017197NIBIB NIH HHS R37 EB001981
6 · The paper itself

Abstract

RATIONALE AND

objectivesThis study aimed to evaluate the technical success rate and stiffness measurement reliability of two specific hepatic magnetic resonance elastography (MRE) sequences dedicated to solving susceptibility artifacts in patients with various degrees of hepatic iron overload. MATERIALS AND

methodsThirty-seven patients with iron-overloaded liver confirmed by R2* value measurement who underwent two-dimensional (2D) spin-echo (SE) MRE and 2D SE-echo-planar-imaging (EPI) MRE were reviewed retrospectively. According to four categories based on R2* value (mild, moderate, severe elevation, and extremely severe iron overload), we compared the success rate, quality score, and liver stiffness of the two sequences. In addition, Spearman's correlation was performed to evaluate the relationship between the R2* value and liver stiffness.

resultsThe overall success rates of SE MRE and SE-EPI MRE in patients with hepatic iron overload were 91.89% and 78.38%, respectively, and 100% and 78.57%, respectively, for severe elevation iron overload. In all patients, the MRE quality scores were 54 and 48 for SE MRE and SE-EPI MRE, respectively (P = 0.107). There were no significant differences in liver stiffness measurements between the two MRE methods in patients with mild, moderate, and severe elevation iron-overloaded livers (P > 0.6 for all), respectively. For both MRE methods, R2* value had no significant effect on the liver stiffness measurements (correlation coefficient <0.1, P >0.6 for both).

conclusionIn the mild and moderate elevation iron-overloaded liver, both SE MRE and fast SE-EPI MRE can provide successful and reliable liver stiffness measurement. In severe elevation iron-overloaded livers, SE MRE may be a better choice than SE-EPI MRE.

Indexed as

Elasticity Imaging TechniquesIron OverloadEcho-Planar ImagingHumansIronLiverLiver CirrhosisMagnetic Resonance ImagingReproducibility of ResultsRetrospective StudiesIronIron overloadMagnetic resonance elastography (MRE)

Identifiers

PMID37863778
PMCPMC12833828

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.