ArticleThe Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation2024
Donation after circulatory death significantly reduces waitlist times while not changing post-heart transplant outcomes: A United Network for Organ Sharing Analysis.
Article in The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 32 citations in OpenAlex.
- Heart-lung transplantation in the United Kingdom: Trends and outcomes over 4 decades.JHLT open · 2026Article
- Article
- Reperfusion Strategies in Donation After Circulatory Death Heart Transplantation: An Up-to-Date Narrative Review.Journal of clinical medicine · 2026Review
- Novel model to predict survival in DCD heart transplants: Development of a mortality risk score using UNOS data.JHLT open · 2026Article
- Donation After Circulatory Death in Pediatric Heart Transplantation.Pediatric transplantation · 2026Article
- Increasing adoption of donation after circulatory death in high-risk heart transplant recipients: Insights into current practices in the United States.JTCVS open · 2026Article
- Implementation of a controlled DCD program in Western Austria - key considerations and insights.Transplant international : official journal of the European Society for Organ Transplantation · 2026Article
- Spanish Center's Early Experience With Donation Following Circulatory Death in Heart Transplantation.ASAIO journal (American Society for Artificial Internal Organs : 1992) · 2026Article
- Listing for Pediatric Donation After Circulatory Death Heart Transplantation Is Associated With Improved Waitlist Outcomes.Journal of the American Heart Association · 2025Article
- Simultaneous Heart and Kidney Transplantation Using Circulatory Death Donors: Are Kidney Graft Outcomes Comparable With Brain Death Donors?Transplantation direct · 2025Article
- Potential intermediate-term survival differences among heart transplant recipients from circulatory death vs brain death donors.JHLT open · 2025Article
- Donation After Circulatory Death following Withdrawal of Life-Sustaining Treatments. Are We Ready to Break the Dead Donor Rule?Journal of bioethical inquiry · 2025Article
- National Organ Procurement and Transplant Network Heart Allocation Policy: 6 Years Later.Circulation. Heart failure · 2025Review
- Early outcomes in heart transplantation using donation after circulatory death donors in patients bridged with durable left ventricular assist devices.The Journal of thoracic and cardiovascular surgery · 2025Article
- Understanding preservation time thresholds in the modern era of heart transplantation.Scientific reports · 2025Article
- The role of temporary mechanical circulatory support in heart failure.European heart journal supplements : journal of the European Society of Cardiology · 2025Article
- Donor Selection for Heart Transplantation in 2025.JACC. Heart failure · 2025Review
- Moderate controlled hypothermiaAnnals of cardiothoracic surgery · 2025Review
- Pediatric heart transplantation in donation after circulatory death: is it a feasible reality?-in time, yes!Annals of cardiothoracic surgery · 2025Article
- Cardiac transplantation in controlled donation after circulatory death: a meta-analysis of long-term survival using reconstructed time-to-event data.Annals of cardiothoracic surgery · 2025Article
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Authors and funding
14 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundRecently, several centers in the United States have begun performing donation after circulatory death (DCD) heart transplants (HTs) in adults. We sought to characterize the recent use of DCD HT, waitlist time, and outcomes compared to donation after brain death (DBD).
methodsUsing the United Network for Organ Sharing database, 10,402 adult (aged >18 years) HT recipients from January 2019 to June 2022 were identified: 425 (4%) were DCD and 9,977 (96%) were DBD recipients. Posttransplant outcomes in matched and unmatched cohorts and waitlist times were compared between groups.
resultsDCD and DBD recipients had similar age (57 years for both, p = 0.791). DCD recipients were more likely White (67% vs 60%, p = 0.002), on left ventricular assist device (LVAD; 40% vs 32%, p < 0.001), and listed as status 4 to 6 (60% vs 24%, p < 0.001); however, less likely to require inotropes (22% vs 40%, p < 0.001) and preoperative extracorporeal membrane oxygenation (0.9% vs 6%, p < 0.001). DCD donors were younger (29 vs 32 years, p < 0.001) and had less renal dysfunction (15% vs 39%, p < 0.001), diabetes (1.9% vs 3.8%, p = 0.050), or hypertension (9.9% vs 16%, p = 0.001). In matched and unmatched cohorts, early survival was similar (p = 0.22). Adjusted waitlist time was shorter in DCD group (21 vs 31 days, p < 0.001) compared to DBD cohort and 5-fold shorter (DCD: 22 days vs DBD: 115 days, p < 0.001) for candidates in status 4 to 6, which was 60% of DCD cohort.
conclusionsThe community is using DCD mostly for those recipients who are expected to have extended waitlist times (e.g., durable LVADs, status >4). DCD recipients had similar posttransplant early survival and shorter adjusted waitlist time compared to DBD group. Given this early success, efforts should be made to expand the donor pool using DCD, especially for traditionally disadvantaged recipients on the waitlist.
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