Evidence map›Paper›PMID 37863116›Full record

ArticleThe American journal of cardiology2024

Pericardial Adipose Tissue Thrombospondin-1 Associates With Antiangiogenesis in Ischemic Heart Disease.

Bulbul Ahmed, Melissa G Farb, Shakun Karki, Sophia D'Alessandro, Niloo M Edwards, Noyan Gokce

Open access · greenAbstract read
In one paragraph

Article in The American journal of cardiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. The Implications of Aging on Vascular Health.International journal of molecular sciences · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Bulbul AhmedEvans Department of Medicine, Boston University School of Medicine, Boston, Massachusetts; Whitaker Cardiovascular Institute, Boston University School of Medicine, Boston, Massachusetts.
Melissa G FarbEvans Department of Medicine, Boston University School of Medicine, Boston, Massachusetts; Whitaker Cardiovascular Institute, Boston University School of Medicine, Boston, Massachusetts.
Shakun KarkiEvans Department of Medicine, Boston University School of Medicine, Boston, Massachusetts; Whitaker Cardiovascular Institute, Boston University School of Medicine, Boston, Massachusetts.
Sophia D'AlessandroEvans Department of Medicine, Boston University School of Medicine, Boston, Massachusetts; Whitaker Cardiovascular Institute, Boston University School of Medicine, Boston, Massachusetts.
Niloo M EdwardsDivision of Cardiac Surgery, Boston Medical Center, Boston, Massachusetts.
Noyan GokceEvans Department of Medicine, Boston University School of Medicine, Boston, Massachusetts; Whitaker Cardiovascular Institute, Boston University School of Medicine, Boston, Massachusetts. Electronic address: Noyan.Gokce@bmc.org.
Boston University · USBoston Medical Center · US

Funding

Wnt signaling control of vascular phenotype in obesityR01HL142650 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI GOKCE, NOYAN, WALSH, KENNETH · 2019 to 2023
$3.1M
Identifying a novel regulatory pathway of vascular function in obesityR01HL140836 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI GOKCE, NOYAN, PURI, VISHWAJEET · 2018 to 2021
$2.2M
Determinants of obesity-associated insulin resistanceK23HL135394 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI FARB, MELISSA G · 2017 to 2021
$895k
NHLBI NIH HHS K23 HL135394NHLBI NIH HHS R01 HL140836NHLBI NIH HHS R01 HL142650
6 · The paper itself

Abstract

Accumulation of ectopic pericardial adipose tissue has been associated with cardiovascular complications which, in part, may relate to adipose-derived factors that regulate vascular responses and angiogenesis. We sought to characterize adipose tissue microvascular angiogenic capacity in subjects who underwent elective cardiac surgeries including aortic, valvular, and coronary artery bypass grafting. Pericardial adipose tissue was collected intraoperatively and examined for angiogenic capacity. Capillary sprouting was significantly blunted (twofold, p <0.001) in subjects with coronary artery disease (CAD) (age 60 ± 9 years, body mass index [BMI] 32 ± 4 kg/m

Indexed as

Coronary Artery DiseaseMyocardial IschemiaAdipose TissueAgedCholesterol, LDLHumansMiddle AgedRNA, MessengerThrombospondin 1Vascular Endothelial Growth Factor ACholesterol, LDLRNA, MessengerThrombospondin 1Vascular Endothelial Growth Factor Aangiogenesiscoronary artery bypass graftingcoronary artery diseaseobesitypericardial adipose tissue

Identifiers

PMID37863116
PMCPMC10842123
OpenAlexW4387745442

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.