Evidence map›Paper›PMID 37862861›Full record

ArticleEnvironment international2023

Air pollution and fecundability in a North American preconception cohort study.

Amelia K Wesselink, Perry Hystad, Kipruto Kirwa, Joel D Kaufman, Mary D Willis, Tanran R Wang, Adam A Szpiro, Jonathan I Levy, David A Savitz, Kenneth J Rothman and 2 more

Abstract read
In one paragraph

Article in Environment international, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Clearing the Air on Reproductive Health: Unpacking the Impact of PMPaediatric and perinatal epidemiology · 2025
    Article
  4. Residential Exposure to PMPaediatric and perinatal epidemiology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Amelia K WesselinkDepartment of Epidemiology, Boston University School of Public Health, Boston, MA, United States. Electronic address: akw23@bu.edu.
Perry HystadSchool of Biological and Population Health Sciences, College of Public Health and Human Sciences, Oregon State University, Corvallis, OR, United States.
Kipruto KirwaDepartment of Environmental & Occupational Health Sciences, School of Public Health, University of Washington, Seattle, WA, United States.
Joel D KaufmanDepartment of Environmental & Occupational Health Sciences, School of Public Health, University of Washington, Seattle, WA, United States.
Mary D WillisDepartment of Epidemiology, Boston University School of Public Health, Boston, MA, United States; School of Biological and Population Health Sciences, College of Public Health and Human Sciences, Oregon State University, Corvallis, OR, United States.
Tanran R WangDepartment of Epidemiology, Boston University School of Public Health, Boston, MA, United States.
Adam A SzpiroDepartment of Biostatistics, School of Public Health, University of Washington, Seattle, WA, United States.
Jonathan I LevyDepartment of Environmental Health, Boston University School of Public Health, Boston, MA, United States.
David A SavitzDepartment of Epidemiology, Brown University School of Public Health, Providence, MA, United States.
Kenneth J RothmanDepartment of Epidemiology, Boston University School of Public Health, Boston, MA, United States.
Elizabeth E HatchDepartment of Epidemiology, Boston University School of Public Health, Boston, MA, United States.
Lauren A WiseDepartment of Epidemiology, Boston University School of Public Health, Boston, MA, United States.

Funding

An internet-based preconception cohort study in North America and DenmarkR01HD086742 · NICHD · BOSTON UNIVERSITY MEDICAL CAMPUS · PI LAUREN A WISE · 2016 to 2026
$6.7M
A preconception cohort study of air pollution, fertility, and miscarriageR01ES028923 · NIEHS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI LAUREN A WISE, Amelia Kent Wesselink · 2018 to 2026
$4.3M
NICHD NIH HHS R01 HD086742NIEHS NIH HHS R01 ES028923
6 · The paper itself

Abstract

backgroundAnimal and epidemiologic studies indicate that air pollution may adversely affect fertility. However, the level of evidence is limited and specific pollutants driving the association are inconsistent across studies.

methodsWe used data from a web-based preconception cohort study of pregnancy planners enrolled during 2013-2019 (Pregnancy Study Online; PRESTO). Eligible participants self-identified as female, were aged 21-45 years, resided in the United States (U.S.) or Canada, and were trying to conceive without fertility treatments. Participants completed a baseline questionnaire and bi-monthly follow-up questionnaires until conception or 12 months. We analyzed data from 8,747 participants (U.S.: 7,304; Canada: 1,443) who had been trying to conceive for < 12 cycles at enrollment. We estimated residential ambient concentrations of particulate matter < 2.5 µm (PM

resultsIn the U.S., the FRs for a 5-µg/m

conclusionsNeither annual average, menstrual cycle-specific, nor preconception average exposure to ambient PM

Indexed as

Air PollutionEnvironmental PollutantsCanadaCohort StudiesFemaleFertilityHumansNitrogen DioxideParticulate MatterPregnancyProspective StudiesUnited StatesEnvironmental PollutantsNitrogen DioxideParticulate MatterAir pollutionFertilityPreconception cohortTime to pregnancy

Identifiers

PMID37862861
PMCPMC10841991

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.