Evidence map›Paper›PMID 37862162›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2024

Association of Cytomegalovirus (CMV) DNAemia With Long-Term Mortality in a Randomized Trial of Preemptive Therapy and Antiviral Prophylaxis for Prevention of CMV Disease in High-Risk Donor Seropositive, Recipient Seronegative Liver Transplant Recipients.

Lakshin Kumar, Sayan Dasgupta, Cristina Murray-Krezan, Nina Singh, Robert M Rakita, Cynthia E Fisher, Ajit P Limaye

Open access · greenAbstract read
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Current and Future Strategies for the Prevention and Treatment of Cytomegalovirus Infections in Transplantation.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2025
    Review
  4. Cytomegalovirus Reactivation Is Associated With Lower Rates of Hepatocellular Carcinoma Recurrence After Liver Transplantation.Transplant international : official journal of the European Society for Organ Transplantation · 2025
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Lakshin KumarDivision of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, Washington, USA.ORCID 0000-0001-9145-1875
Sayan DasguptaVaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, Washington, USA.ORCID 0000-0001-5271-7247
Cristina Murray-KrezanDivision of General Internal Medicine, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Nina SinghDepartment of Medicine, VA Pittsburgh Healthcare System and University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Robert M RakitaDivision of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, Washington, USA.
Cynthia E FisherDivision of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, Washington, USA.
Ajit P LimayeDivision of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, Washington, USA.ORCID 0000-0002-5350-9025
University of Washington · USUniversity of Pittsburgh · USFred Hutch Cancer Center · US

Funding

Cytomegalovirus (CMV) Vaccine in Orthotopic Liver Transplant candidates (COLT)U01AI163090 · NIAID · UNIVERSITY OF WASHINGTON · PI Don J Diamond, Cynthia E Fisher · 2021 to 2026
$17.4M
Respiratory Viral Determinants of Chronic Lung Allograft DysfunctionK23HL143050 · NHLBI · UNIVERSITY OF WASHINGTON · PI FISHER, CYNTHIA E · 2018 to 2022
$986k
NHLBI NIH HHS K23 HL143050NIAID NIH HHS U01 AI163090NIH HHS U01 AI63098
6 · The paper itself

Abstract

In a post-hoc analysis of the association of CMV DNAemia with long-term mortality in a randomized trial of CMV preemptive therapy vs. antiviral prophylaxis in D+R- liver transplant recipients, post-intervention CMV DNAemia was associated with increased mortality after adjusting for study arm.

Indexed as

Cytomegalovirus InfectionsLiver TransplantationAntiviral AgentsCytomegalovirusHumansRandomized Controlled Trials as TopicTissue DonorsTransplant RecipientsAntiviral Agentsantiviral therapycytomegalovirusimmunocompromised hostliver transplantviral infections

Identifiers

PMID37862162
PMCPMC10954330
OpenAlexW4387800551

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.