Evidence map›Paper›PMID 37861900›Full record

ArticleBulletin of experimental biology and medicine2023

In Vivo and In Vitro Analysis of Toxicity of a Prospective Magnetic Resonance Contrast Agent Based on Arabinogalactan and Gadolinium Nanocomposite.

V A Tyutrina, E S Andreeva, E A Titov, V A Vokina, M A Novikov, L M Sosedova

Abstract read
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Article in Bulletin of experimental biology and medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 92% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

V A TyutrinaSiberian Institute of Medical and Environmental Research, Angarsk, Russia. tyutrina.v.a@yandex.ru.
E S AndreevaSiberian Institute of Medical and Environmental Research, Angarsk, Russia.
E A TitovSiberian Institute of Medical and Environmental Research, Angarsk, Russia.
V A VokinaSiberian Institute of Medical and Environmental Research, Angarsk, Russia.
M A NovikovSiberian Institute of Medical and Environmental Research, Angarsk, Russia.
L M SosedovaSiberian Institute of Medical and Environmental Research, Angarsk, Russia.
East-Siberian Institute of Medical and Ecological Research · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We studied the cytotoxic effect of gadolinium nanocomposite on cultured mouse fibroblasts 3T3-SV40 and histological changes in the liver tissue of albino rats after its administration. For in vitro experiment, gadolinium nanocomposite on the natural matrix of arabinogalactan (nGd-AG) was dissolved in DMEM nutrient medium to concentrations of 0.005, 0.02, 0.5, 2, and 5 mM. In in vivo experiment, a nGd-AG solution was orally administered to rats through a tube in a dose of 500 μg Gd/kg in 1 ml of 0.9% NaCl for 10 days. The pattern and degree of influence of the gadolinium nanocomposite on the studied cell culture depended on the concentration and duration of exposure. IC

Indexed as

Contrast MediaNanocompositesAnimalsGadoliniumGalactansMagnetic Resonance ImagingMagnetic Resonance SpectroscopyMiceProspective StudiesRatsarabinogalactanContrast MediaGadoliniumGalactansarabinogalactancell culturecytotoxicitygadolinium nanocompositeliver

Identifiers

PMID37861900
OpenAlexW4387798358

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.