Evidence map›Paper›PMID 37861651›Full record

ArticleAmerican journal of physiology. Heart and circulatory physiology2023

Adjusting for muscle strength and body size attenuates sex differences in the exercise pressor reflex in young adults.

McKenna A Tharpe, Braxton A Linder, Matthew C Babcock, Joseph C Watso, Kamila U Pollin, Zach J Hutchison, Alex M Barnett, Meral N Culver, Andreas N Kavazis, Michael S Brian and 1 more

Erratum issuedOpen access · greenAbstract read
In one paragraph

Article in American journal of physiology. Heart and circulatory physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.2field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

McKenna A TharpeNeurovascular Physiology Laboratory, School of Kinesiology, Auburn University, Auburn, Alabama, United States.ORCID 0000-0002-3868-1564
Braxton A LinderNeurovascular Physiology Laboratory, School of Kinesiology, Auburn University, Auburn, Alabama, United States.ORCID 0000-0001-6825-5622
Matthew C BabcockDepartment of Kinesiology and Applied Physiology, University of Delaware, Newark, Delaware, United States.ORCID 0000-0002-8047-4411
Joseph C WatsoDepartment of Kinesiology and Applied Physiology, University of Delaware, Newark, Delaware, United States.ORCID 0000-0001-7840-0643
Kamila U PollinDepartment of Kinesiology and Applied Physiology, University of Delaware, Newark, Delaware, United States.
Zach J HutchisonNeurovascular Physiology Laboratory, School of Kinesiology, Auburn University, Auburn, Alabama, United States.
Alex M BarnettNeurovascular Physiology Laboratory, School of Kinesiology, Auburn University, Auburn, Alabama, United States.ORCID 0009-0009-3650-2655
Meral N CulverNeurovascular Physiology Laboratory, School of Kinesiology, Auburn University, Auburn, Alabama, United States.ORCID 0000-0003-1652-1639
Andreas N KavazisNeurovascular Physiology Laboratory, School of Kinesiology, Auburn University, Auburn, Alabama, United States.ORCID 0000-0002-2535-7490
Michael S BrianDepartment of Kinesiology and Applied Physiology, University of Delaware, Newark, Delaware, United States.
Austin T RobinsonNeurovascular Physiology Laboratory, School of Kinesiology, Auburn University, Auburn, Alabama, United States.ORCID 0000-0001-8250-3952
Auburn University · USFlorida State University · USUniversity of Colorado Anschutz Medical Campus · USUniversity of New Hampshire · USVeterans Health Administration · US

Funding

National Dissemination of I-Corps@NCATS: Accelerating Translation through CommercializationUL1TR003096 · NCATS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI GUTIERREZ, ORLANDO M, KIMBERLY, ROBERT P. · 2019 to 2023
$43.6M
Adverse Neurogenic Actions of Dietary SaltR01HL128388 · NHLBI · UNIVERSITY OF DELAWARE · PI FARQUHAR, WILLIAM B, STOCKER, SEAN D · 2016 to 2019
$2.6M
Racial Differences in Serum Sodium and Blood Pressure RegulationK01HL147998 · NHLBI · TRUSTEES OF INDIANA UNIVERSITY · PI ROBINSON, AUSTIN TYLER · 2019 to 2023
$705k
Time-Efficient Inspiratory Muscle Strength Training as a New Approach to Lower Blood Pressure, Improve Respiratory Function, and Reduce Exertional Dyspnea in Adults with ObesityK01HL160772 · NHLBI · FLORIDA STATE UNIVERSITY · PI Joseph Watso · 2022 to 2026
$693k
Neural and Renal Contributions to Hypertension with Androgen Deprivation TherapyK01HL164978 · NHLBI · VIRGINIA COMMONWEALTH UNIVERSITY · PI Matthew C Babcock · 2023 to 2026
$665k
Mitochondria Dysfunction as a Contributor to Racial Disparities in Vascular Health and HypertensionR15HL165325 · NHLBI · AUBURN UNIVERSITY AT AUBURN · PI KAVAZIS, ANDREAS N · 2022 to 2022
$439k
NCATS NIH HHS UL1 TR003096NHLBI NIH HHS K01 HL147998NHLBI NIH HHS K01 HL160772NHLBI NIH HHS K01 HL164978NHLBI NIH HHS R01 HL128388NHLBI NIH HHS R15 HL165325
6 · The paper itself

Abstract

Females typically exhibit lower blood pressure (BP) during exercise than males. However, recent findings indicate that adjusting for maximal strength attenuates sex differences in BP during isometric handgrip (HG) exercise and postexercise ischemia (PEI; metaboreflex isolation). In addition, body size is associated with HG strength but its contribution to sex differences in exercising BP is less appreciated. Therefore, the purpose of this study was to determine whether adjusting for strength and body size would attenuate sex differences in BP during HG and PEI. We obtained beat-to-beat BP in 110 participants (36 females, 74 males) who completed 2 min of isometric HG exercise at 40% of their maximal voluntary contraction followed by 3 min of PEI. In a subset (11 females, 17 males), we collected muscle sympathetic nerve activity (MSNA). Statistical analyses included independent

Indexed as

Hand StrengthSex CharacteristicsBlood PressureBody SizeFemaleHeart RateHumansIschemiaMaleMuscle, SkeletalReflexSympathetic Nervous SystemYoung Adultautonomic functionblood pressurecardiovascular diseasecardiovascular physiologyexercise

Identifiers

PMID37861651
PMCPMC10907031
OpenAlexW4387798138

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.