Evidence map›Paper›PMID 37861312›Full record

ArticleInfection and immunity2023

Dectin-1/CARD9 induction of the TFEB and TFE3 gene network is dispensable for phagocyte anti-

Mariano A Aufiero, Neta Shlezinger, Mergim Gjonbalaj, Kathleen A M Mills, Andrea Ballabio, Tobias M Hohl

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Infection and immunity, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Mariano A AufieroLouis V. Gerstner Jr. Graduate School of Biomedical Sciences, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center , New York, New York, USA.ORCID 0000-0003-2462-438X
Neta ShlezingerKoret School of Veterinary Medicine, The Robert H. Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem , Rehovot, Israel.
Mergim GjonbalajInfectious Disease Service, Department of Medicine, Memorial Hospital , New York, New York, USA.
Kathleen A M MillsImmunology and Microbial Pathogenesis Graduate Program, Weill Cornell Graduate School , New York, New York, USA.
Andrea BallabioTelethon Institute of Genetics and Medicine (TIGEM) , Pozzuoli, Italy.
Tobias M HohlLouis V. Gerstner Jr. Graduate School of Biomedical Sciences, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center , New York, New York, USA.ORCID 0000-0002-9097-5412
Memorial Sloan Kettering Cancer Center · USBaylor College of Medicine · USCornell University · USHebrew University of Jerusalem · IL

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
INITIATION OF THE IMMUNE RESPONSE TO ASPERGILLUS FUMIGATUSR01AI093808 · NIAID · SLOAN-KETTERING INST CAN RESEARCH · PI HOHL, TOBIAS M · 2011 to 2020
$4.9M
INITIATION OF THE IMMUNE RESPONSE TO ASPERGILLUS FUMIGATUSR37AI093808 · NIAID · SLOAN-KETTERING INST CAN RESEARCH · PI TOBIAS M HOHL · 2021 to 2026
$4.2M
Antifungal Immunity and the Mechanism of Fungal Programmed Cell DeathR01AI139632 · NIAID · SLOAN-KETTERING INST CAN RESEARCH · PI CRAMER, ROBERT ANDREW, HOHL, TOBIAS M · 2019 to 2023
$3.3M
IL-1 signaling in defense against Aspergillus fumigatus infectionF31AI167511 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI MILLS, KATHLEEN · 2022 to 2024
$143k
Deciphering the Role of Lysosomal Biogenesis in Anti-Aspergillus Immune ResponsesF31AI161996 · NIAID · SLOAN-KETTERING INST CAN RESEARCH · PI AUFIERO, MARIANO ALEJANDRO · 2021 to 2023
$140k
NCI NIH HHS P30 CA008748NIAID NIH HHS F31 AI161996NIAID NIH HHS F31 AI167511NIAID NIH HHS R01 AI093808NIAID NIH HHS R01 AI139632NIAID NIH HHS R37 AI093808
6 · The paper itself

Abstract

Myeloid phagocytes of the respiratory immune system, such as neutrophils, monocytes, and alveolar macrophages, are essential for immunity to

Indexed as

AspergillosisPneumoniaAnimalsAspergillus fumigatusBasic Helix-Loop-Helix Leucine Zipper Transcription FactorsCARD Signaling Adaptor ProteinsDectin-1Gene Regulatory NetworksLungMicePhagocytesBasic Helix-Loop-Helix Leucine Zipper Transcription FactorsCard9 protein, mouseCARD Signaling Adaptor ProteinsDectin-1Tcfe3 protein, mouseTcfeb protein, mouseAspergillus fumigatusFungusInnate ImmunityLungLysosomeTFE3TFEB

Identifiers

PMID37861312
PMCPMC10652993
OpenAlexW4387798928

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.