Evidence map›Paper›PMID 37860983›Full record

ArticleThe Laryngoscope2024

Panitumumab-IRDye800 Improves Laryngeal Tumor Mapping During Transoral Laser Microsurgery.

Luke Bailey, Logan D Stone, Manuel L Gonzalez, Carissa M Thomas, Hari Jeyarajan, Jason M Warram, Bharat Panuganti

Open access · greenAbstract readCase Reports
In one paragraph

Article in The Laryngoscope, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Exploring the landscape of AI-assisted decision-making in head and neck cancer treatment: a comparative analysis of NCCN guidelines and ChatGPT responses.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Luke BaileyDepartment of Otolaryngology, University of Alabama at Birmingham, Birmingham, Alabama, USA.ORCID 0009-0009-8555-7900
Logan D StoneDepartment of Otolaryngology, University of Alabama at Birmingham, Birmingham, Alabama, USA.ORCID 0000-0002-5802-8888
Manuel L GonzalezDepartment of Pathology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Carissa M ThomasDepartment of Otolaryngology, University of Alabama at Birmingham, Birmingham, Alabama, USA.ORCID 0000-0003-0765-5731
Hari JeyarajanDepartment of Otolaryngology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Jason M WarramDepartment of Otolaryngology, University of Alabama at Birmingham, Birmingham, Alabama, USA.ORCID 0000-0001-5230-0011
Bharat PanugantiDepartment of Otolaryngology, University of Alabama at Birmingham, Birmingham, Alabama, USA.ORCID 0000-0003-1149-9532
University of Alabama at Birmingham · US

Funding

Reduction of Tumor-Positive Margins in Oncology SurgeryR37CA245157 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Jason Morgan Warram · 2021 to 2026
$3.2M
Combination optical imaging to guide transoral laser microsurgery in larynx cancerR21CA292196 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI PANUGANTI, BHARAT, WARRAM, JASON MORGAN · 2024 to 2024
$375k
NCI NIH HHS R21 CA292196NCI NIH HHS R37 CA245157
6 · The paper itself

Abstract

Transoral laser microsurgery represents the primary surgical modality for early laryngeal cancers with oncologic outcomes equivalent to radiotherapy. Accurate tumor mapping and margin assessment can be difficult, however, particularly during piecemeal or ablative resections, and for tumors with a wider geographic footprint. Tumor-targeted fluorescence-guided surgery in patients with head and neck cancer has empirically improved tumor and margin identification; this case details, for the first time, a fluorescence-guided surgical resection of a T2N0M0 transglottic tumor using panitumumab-IRDye800, an epidermal growth factor receptor monoclonal antibody covalently linked to near-infrared (NIR) dye. Laryngoscope, 134:1837-1841, 2024.

Indexed as

Carcinoma, Squamous CellIndolesLaryngeal NeoplasmsLaser TherapyGlottisHumansLasersMicrosurgeryNeoplasm StagingPanitumumabRetrospective StudiesIndolesIRDye800Panitumumabearly glottic carcinomafluorescence-guided surgerymargintransoral laser microsurgery

Identifiers

PMID37860983
PMCPMC10947975
OpenAlexW4387799162

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.