Evidence map›Paper›PMID 37860701›Full record

ReviewEuropean cardiology2023

Percutaneous Left Atrial Appendage Occlusion: What the Practising Physician Should Know.

Pierluigi Merella, Giuseppe Talanas, Giovanni Lorenzoni, Cristiana Denurra, Enrico Atzori, Gavino Casu

Abstract readReview
In one paragraph

Review in European cardiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Left atrial appendage occlusion: behind the bleeding risk.European heart journal supplements : journal of the European Society of Cardiology · 2025
    Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Pierluigi MerellaDepartment of Cardiology, Azienda Ospedaliero Universitaria di Sassari Sassari, Italy.
Giuseppe TalanasDepartment of Cardiology, Azienda Ospedaliero Universitaria di Sassari Sassari, Italy.
Giovanni LorenzoniDepartment of Cardiology, Azienda Ospedaliero Universitaria di Sassari Sassari, Italy.
Cristiana DenurraDepartment of Cardiology, Azienda Ospedaliero Universitaria di Sassari Sassari, Italy.
Enrico AtzoriDepartment of Cardiology, Azienda Ospedaliero Universitaria di Sassari Sassari, Italy.
Gavino CasuDepartment of Cardiology, Azienda Ospedaliero Universitaria di Sassari Sassari, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-valvular AF is a common clinical condition associated with an increased risk of thromboembolic complications. As a consequence, oral anticoagulant therapy (OAT) is the cornerstone of non-valvular AF management. Despite the well-established efficacy of OAT, many patients cannot receive this preventive therapy due to bleeding or a high risk of bleeding. The fact that more than 90% of thrombi are formed in the left atrial appendage has led to the development of alternative methods to reduce the embolic risk. Left atrial appendage occlusion (LAAO) is a non-pharmacological option for preventing cardioembolic events in patients with non-valvular AF with a contraindication to OAT. The demand for LAAO procedures is growing exponentially and clinicians should consider this alternative option when managing patients with a contraindication to OAT. This review summarises the current thinking about LAAO.

Indexed as

AFbleedinghigh bleeding riskleft atrial appendage occlusion

Identifiers

PMID37860701
PMCPMC10583154

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.