Evidence map›Paper›PMID 37860689›Full record

ArticleiScience2023

A novel APA-based prognostic signature may predict the prognosis of lung adenocarcinoma in an East Asian population.

Wendi Zhang, Yang Hu, Min Qian, Liping Mao, Yanqiong Yuan, Huiwen Xu, Yiran Liu, Anni Qiu, Yan Zhou, Yang Dong and 7 more

Abstract read
In one paragraph

Article in iScience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Mitochondrial function meets oncology: the multifaceted role of TFAM across cancer types.Apoptosis : an international journal on programmed cell death · 2026
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  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Wendi ZhangDepartment of Epidemiology, School of Public Health, Nantong University, Nantong, Jiangsu, China.
Yang HuDepartment of Epidemiology, School of Public Health, Nantong University, Nantong, Jiangsu, China.
Min QianDepartment of Epidemiology, School of Public Health, Nantong University, Nantong, Jiangsu, China.
Liping MaoDepartment of Oncology, Affiliated Nantong Hospital of Shanghai University (The Sixth People's Hospital of Nantong), Nantong, Jiangsu, China.
Yanqiong YuanDepartment of Epidemiology, School of Public Health, Nantong University, Nantong, Jiangsu, China.
Huiwen XuDepartment of Epidemiology, School of Public Health, Nantong University, Nantong, Jiangsu, China.
Yiran LiuDepartment of Epidemiology, School of Public Health, Nantong University, Nantong, Jiangsu, China.
Anni QiuDepartment of Epidemiology, School of Public Health, Nantong University, Nantong, Jiangsu, China.
Yan ZhouDepartment of Epidemiology, School of Public Health, Nantong University, Nantong, Jiangsu, China.
Yang DongDepartment of Epidemiology, School of Public Health, Nantong University, Nantong, Jiangsu, China.
Yutong WuDepartment of Epidemiology, School of Public Health, Nantong University, Nantong, Jiangsu, China.
Qiong ChenDepartment of Epidemiology, School of Public Health, Nantong University, Nantong, Jiangsu, China.
Xiaobo TaoDepartment of Epidemiology, School of Public Health, Nantong University, Nantong, Jiangsu, China.
Tian TianDepartment of Epidemiology, School of Public Health, Nantong University, Nantong, Jiangsu, China.
Lei ZhangDepartment of Epidemiology, School of Public Health, Nantong University, Nantong, Jiangsu, China.
Jiahua CuiDepartment of Epidemiology, School of Public Health, Nantong University, Nantong, Jiangsu, China.
Minjie ChuDepartment of Epidemiology, School of Public Health, Nantong University, Nantong, Jiangsu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The role of alternative polyadenylation (APA) in tumor development is becoming increasingly evident, but the impact of APA events on the prognosis of LUAD patients is unclear. Therefore, in the present study, we aimed to analyze specific APA events in LUAD to identify novel prognostic biomarkers for LUAD. We first identified prognostic candidate genes for LUAD associated with APA events and validated them in both the East Asian and the USA cohorts, finding that five genes (

Indexed as

BiochemistryMedical sciencePhysiology

Identifiers

PMID37860689
PMCPMC10583048

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.