Evidence map›Paper›PMID 37860269›Full record

ReviewNeuro-oncology advances

Evolution and implementation of radiographic response criteria in neuro-oncology.

Divya Ramakrishnan, Marc von Reppert, Mark Krycia, Matthew Sala, Sabine Mueller, Sanjay Aneja, Ali Nabavizadeh, Norbert Galldiks, Philipp Lohmann, Cyrus Raji and 4 more

Abstract readReview
In one paragraph

Review in Neuro-oncology advances. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Observational
  3. Bevacizumab in Pediatric Neuro-Oncology.Current oncology (Toronto, Ont.) · 2025
    Review
  4. Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Divya RamakrishnanDepartment of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, Connecticut, USA.ORCID https://orcid.org/0000-0003-2581-1793
Marc von ReppertDepartment of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, Connecticut, USA.
Mark KryciaDepartment of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, Connecticut, USA.
Matthew SalaDepartment of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, Connecticut, USA.
Sabine MuellerDepartment of Neurology, Neurosurgery, and Pediatrics, University of California San Francisco, San Francisco, California, USA.
Sanjay AnejaDepartment of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, Connecticut, USA.
Ali NabavizadehDepartment of Radiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA.ORCID https://orcid.org/0000-0002-0380-4552
Norbert GalldiksDepartment of Neurology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.ORCID https://orcid.org/0000-0002-2485-1796
Philipp LohmannInstitute of Neuroscience and Medicine (INM-4), Research Center Juelich, Juelich, Germany.ORCID https://orcid.org/0000-0002-5360-046X
Cyrus RajiDepartment of Radiology, Washington University in St. Louis School of Medicine, St. Louis, Missouri, USA.
Ichiro IkutaDepartment of Radiology, Mayo Clinic, Phoenix, Arizona, USA.
Fatima MemonDepartment of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, Connecticut, USA.
Brent D WeinbergDepartment of Radiology, Emory University School of Medicine, Atlanta, Georgia, USA.
Mariam S AboianDepartment of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, Connecticut, USA.ORCID https://orcid.org/0000-0002-4877-8271

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Radiographic response assessment in neuro-oncology is critical in clinical practice and trials. Conventional criteria, such as the MacDonald and response assessment in neuro-oncology (RANO) criteria, rely on bidimensional (2D) measurements of a single tumor cross-section. Although RANO criteria are established for response assessment in clinical trials, there is a critical need to address the complexity of brain tumor treatment response with multiple new approaches being proposed. These include volumetric analysis of tumor compartments, structured MRI reporting systems like the Brain Tumor Reporting and Data System, and standardized approaches to advanced imaging techniques to distinguish tumor response from treatment effects. In this review, we discuss the strengths and limitations of different neuro-oncology response criteria and summarize current research findings on the role of novel response methods in neuro-oncology clinical trials and practice.

Indexed as

BT-RADSRANORAPNOResponse AssessmentVolumetrics

Identifiers

PMID37860269
PMCPMC10584081

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.