Evidence map›Paper›PMID 37860203›Full record

ArticleThe Lancet regional health. Western Pacific2023

Community-wide versus school-based targeted deworming for soil-transmitted helminth control in school-aged children in Vietnam: the CoDe-STH cluster-randomised controlled trial.

Clare E F Dyer, Dinh Ng-Nguyen, Naomi E Clarke, Sze Fui Hii, Hieu Quoc Nguyen, Van-Anh Thi Nguyen, Thai Van Nguyen, Trong Van Nguyen, Tam Thi Ngo, H M P Dilrukshi Herath and 9 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Lancet regional health. Western Pacific, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 7 institutions in 4 countries.

Clare E F DyerThe Kirby Institute, University of New South Wales, Sydney, NSW, Australia.
Dinh Ng-NguyenFaculty of Animal Sciences and Veterinary Medicine, Tay Nguyen University, Dak Lak, Vietnam.
Naomi E ClarkeThe Kirby Institute, University of New South Wales, Sydney, NSW, Australia.
Sze Fui HiiFaculty of Science, Melbourne Veterinary School, The University of Melbourne, Melbourne, Vic, Australia.
Hieu Quoc NguyenFaculty of Animal Sciences and Veterinary Medicine, Tay Nguyen University, Dak Lak, Vietnam.
Van-Anh Thi NguyenFaculty of Animal Sciences and Veterinary Medicine, Tay Nguyen University, Dak Lak, Vietnam.
Thai Van NguyenFaculty of Animal Sciences and Veterinary Medicine, Tay Nguyen University, Dak Lak, Vietnam.
Trong Van NguyenFaculty of Animal Sciences and Veterinary Medicine, Tay Nguyen University, Dak Lak, Vietnam.
Tam Thi NgoCenters for Disease Control and Prevention, Dak Lak, Vietnam.
H M P Dilrukshi HerathFaculty of Science, Melbourne Veterinary School, The University of Melbourne, Melbourne, Vic, Australia.
Handan WandThe Kirby Institute, University of New South Wales, Sydney, NSW, Australia.
Luc E CoffengDepartment of Public Health, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.
Justine C MarshallThe Kirby Institute, University of New South Wales, Sydney, NSW, Australia.
Darren J GrayResearch School of Population Health, Australian National University, Canberra, ACT, Australia.
Roy M AndersonFaculty of Medicine, School of Public Health, Imperial College London, London, United Kingdom.
Archie C A ClementsFaculty of Health Sciences, Curtin University, Perth, WA, Australia.
John M KaldorThe Kirby Institute, University of New South Wales, Sydney, NSW, Australia.
Rebecca J TraubFaculty of Science, Melbourne Veterinary School, The University of Melbourne, Melbourne, Vic, Australia.
Susana Vaz NeryThe Kirby Institute, University of New South Wales, Sydney, NSW, Australia.
UNSW Sydney · AUThai Nguyen University · VNThe University of Melbourne · AUAustralian National University · AUErasmus MC · NLImperial College London · GBThe Kids Research Institute Australia · AU

Funding

Medical Research Council MR/R015600/1Medical Research Council MR/X020258/1
6 · The paper itself

Abstract

Background: Soil-transmitted helminth (STH) infection control programs typically consist of school-based preventive chemotherapy (PC) targeted to school-aged children. STH reservoirs in untreated community members contribute to ongoing transmission in children. The CoDe-STH (Community Deworming against STH) trial, conducted in Dak Lak province, Vietnam, between October 2019 and November 2020, aimed to determine whether community-wide mass drug administration (MDA) is more effective than school-based targeted PC in reducing STH prevalence and intensity in children. Methods: In this two-arm cluster randomised controlled trial, 64 primary schools were randomly assigned 1:1 to receive either school-based targeted PC ("school arm") or community-wide MDA ("community arm"). A single dose of albendazole 400 mg was used for deworming. The primary outcome was hookworm prevalence in schoolchildren, measured using quantitative real-time PCR. We also measured infection intensity for Findings: The analysis included 4955 children in the school arm and 5093 children in the community arm. Interpretation: Although no impact was seen on overall prevalence, community-wide MDA was more effective in lowering Funding: National Health and Medical Research Council, Australia (APP1139561).

Indexed as

DewormingHookwormMass drug administrationSoil-transmitted helminthsTargeted preventive chemotherapy

Identifiers

PMID37860203
PMCPMC10583164
OpenAlexW4387556924

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.