Evidence map›Paper›PMID 37860079›Full record

ArticleAdvances in oncology2023

Advances in Blood-Brain Barrier Disruption to Facilitate Drug Delivery for Infiltrative Gliomas.

Andrew Gould, Victor Andrés Arrieta Gonzales, Crismita Clement Dmello, Ruth Saganty, Rimas V Lukas, Daniel Y Zhang, Amy B Heimberger, Michael Canney, Alexandre Carpentier, Carole Desseaux and 3 more

Abstract read
In one paragraph

Article in Advances in oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Pharmacokinetic Analysis of Carboplatin and Fluorescein Brain Retention following Ultrasound-Based Blood-Brain Barrier Opening.Clinical cancer research : an official journal of the American Association for Cancer Research · 2025
    Trial
  2. Review
  3. CAR-T cells immunotherapy in the treatment of glioblastoma.Cancer immunology, immunotherapy : CII · 2025
    Review
  4. Review
  5. Review
  6. Immunotherapy in Glioblastoma.Cancer treatment and research · 2025
    Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Paclitaxel and Carboplatin in Combination with Low-intensity Pulsed Ultrasound for Glioblastoma.Clinical cancer research : an official journal of the American Association for Cancer Research · 2024
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Andrew GouldDepartment of Neurosurgery, Northwestern University, Feinberg School of Medicine, Chicago Illinois.
Victor Andrés Arrieta GonzalesDepartment of Neurosurgery, Northwestern University, Feinberg School of Medicine, Chicago Illinois.
Crismita Clement DmelloDepartment of Neurosurgery, Northwestern University, Feinberg School of Medicine, Chicago Illinois.
Ruth SagantyDepartment of Neurosurgery, Northwestern University, Feinberg School of Medicine, Chicago Illinois.
Rimas V LukasNorthwestern Medicine Malnati Brain Tumor Institute of the Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago Illinois.
Daniel Y ZhangDepartment of Neurosurgery, Northwestern University, Feinberg School of Medicine, Chicago Illinois.
Amy B HeimbergerDepartment of Neurosurgery, Northwestern University, Feinberg School of Medicine, Chicago Illinois.
Michael CanneyCarthera, Lyon France.
Alexandre CarpentierAP-HP, Neurosurgery Department, Hôpital Pitie Salpetriere, F-75013, Paris, France.
Carole DesseauxCarthera, Lyon France.
Guillaume BouchouxCarthera, Lyon France.
Roger StuppDepartment of Neurosurgery, Northwestern University, Feinberg School of Medicine, Chicago Illinois.
Adam M SonabendDepartment of Neurosurgery, Northwestern University, Feinberg School of Medicine, Chicago Illinois.

Funding

STINGing GBM: A First-in- Man Clinical Trial in Surgical Resectable Recurrent GBMP50CA221747 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Pouya Jamshidi · 2018 to 2026
$21.4M
Leveraging doxorubicin immune-modulation, blood-brain barrier opening, and personalized medicine for effective immunotherapy in glioblastoma. A mechanistic approach and pharmacokinetic trial.U19CA264338 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Nicholas A Butowski · 2021 to 2026
$5.8M
Blood-brain barrier disruption with implantable ultrasound to enhance paclitaxel delivery: A Phase 1-2 clinical trial in recurrent glioblastomaR01CA245969 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Adam M Sonabend, Roger Stupp · 2020 to 2026
$2.8M
MAPK as target of glioma immunoediting by CD8 T-cells, and predictor of response to immunotherapyR01NS110703 · NINDS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI SONABEND, ADAM M · 2020 to 2024
$1.9M
NCI NIH HHS P50 CA221747NCI NIH HHS R01 CA245969NCI NIH HHS U19 CA264338NINDS NIH HHS R01 NS110703
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID37860079
PMCPMC10583833

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.