ArticleFrontiers in endocrinology2023
The relationship between sarcopenia and mortality in Chinese community-dwelling adults: a 7-year cohort study with propensity score matching and Mendelian randomization.
Article in Frontiers in endocrinology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 15 citations in OpenAlex.
- Combined Effect of Sarcopenia and Impaired Respiratory Function on All-Cause Death: A Nationwide Cohort Study.Journal of cachexia, sarcopenia and muscle · 2026Article
- Declines in Activities in Daily Living of Older Adults with Sarcopenia Were Associated with Gait Speed.Medicina (Kaunas, Lithuania) · 2026Article
- A body shape index and sarcopenia risk in middle-aged and older adults: evidence from the China Health and Retirement Longitudinal Study.European journal of medical research · 2025Article
- Association of possible sarcopenia and its components with all-cause mortality in a middle-aged and older population: a 9-year cohort study.Scientific reports · 2025Article
- Interactions between bone density and muscle mass in predicting all-cause mortality: a 10-year prospective cohort study of 1388 older men (aged 77-101 years).Age and ageing · 2025Article
- Article
- Construct prediction models for low muscle mass with metabolic syndrome using machine learning.PloS one · 2025Article
- Changes in sarcopenia and incident cardiovascular disease in prospective cohorts.BMC medicine · 2024Article
- Cystatin C Is a Predictor for Long-Term, All-Cause, and Cardiovascular Mortality in US Adults With Metabolic Syndrome.The Journal of clinical endocrinology and metabolism · 2024Article
- Exploring the Molecular Adaptations, Benefits, and Future Direction of Exercise Training: Updated Insights into Cardiovascular Health.Journal of functional morphology and kinesiology · 2024Review
- Association of Handgrip Strength with Hip Fracture and Falls in Community-dwelling Middle-aged and Older Adults: A 4-Year Longitudinal Study.Orthopaedic surgery · 2024Article
- Prevalence and Risk Factors of Sarcopenia in Community-Dwelling Older Adults: A Cross-Sectional Study With Nutritional Assessment.Inquiry : a journal of medical care organization, provision and financingArticle
Corrections and comments
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Authors and funding
15 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Sarcopenia has been linked to adverse health outcomes, including an increased risk of mortality. This study aimed to assess the 7-year mortality risk of sarcopenia in a community-based population in China and explore the causal relationship between components of sarcopenia and any death. Methods: Data were sourced from the China Health and Retirement Longitudinal Study (CHARLS) conducted between 2011 and 2018. Sarcopenia was diagnosed using the Asian Working Group for Sarcopenia (AWGS) 2019 criteria. Logistic regression, Kaplan-Meier (KM) survival analysis, and propensity score matching with inverse probability of treatment weighting were used. Mendelian randomization (MR) analyses, conducted using European population data, were utilized to assess causality between sarcopenia and any death. Results: The study included 9,006 participants: 3,892 had no sarcopenia, 3,570 had possible sarcopenia, 1,125 had sarcopenia, and 419 had severe sarcopenia. Over 7 years of follow-up, there were 871 deaths, including 196 with sarcopenia and 133 with severe sarcopenia. The KM curves showed that sarcopenia had a higher risk of mortality. Compared to those of no sarcopenia, the odds ratios (ORs) of sarcopenia for 7-year mortality were 1.41 (95% CI, 1.06-1.87) after adjusting for confounding variables ( Conclusion: This study underscores the significant impact of sarcopenia and its components on mortality risk within the Chinese population. Particularly, low hand grip strength and usual walking pace emerged as noteworthy contributors to mortality risk.
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