Evidence map›Paper›PMID 37858440›Full record

ReviewTrends in neurosciences2023

The making of a proprioceptor: a tale of two identities.

Joriene C de Nooij, Niccolò Zampieri

Abstract readReview
In one paragraph

Review in Trends in neurosciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. A who's who of cell types in skeletal muscle.Communications biology · 2026
    Review
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  5. Review
  6. Review
  7. Article
  8. Article
  9. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Joriene C de NooijDepartment of Neurology, Division of Translational Neurobiology, Vagelos College of Physicians and Surgeons, 650 West 168th Street, New York, NY 10032, USA; Columbia University Motor Neuron Center, Columbia University Medical Center, 630 West 168th Street, New York, NY 10032, USA. Electronic address: sd382@cumc.columbia.edu.
Niccolò ZampieriMax-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Robert-Rössle-Strasse 10, 13125 Berlin, Germany. Electronic address: niccolo.zampieri@mdc-berlin.de.

Funding

Molecular Dissection of Proprioceptor Subclass IdentityR01NS106715 · NINDS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Joriene De Nooij · 2019 to 2026
$3.0M
National Institute of Neurological Disorders and Stroke (NINDS) [National Institutes of Health (NIH) R01NS106715NINDS NIH HHS R01 NS106715
6 · The paper itself

Abstract

Proprioception, the sense of body position in space, has a critical role in the control of posture and movement. Aside from skin and joint receptors, the main sources of proprioceptive information in tetrapods are mechanoreceptive end organs in skeletal muscle: muscle spindles (MSs) and Golgi tendon organs (GTOs). The sensory neurons that innervate these receptors are divided into subtypes that detect discrete aspects of sensory information from muscles with different biomechanical functions. Despite the importance of proprioceptive neurons in motor control, the developmental mechanisms that control the acquisition of their distinct functional properties and positional identity are not yet clear. In this review, we discuss recent findings on the development of mouse proprioceptor subtypes and challenges in defining them at the molecular and functional level.

Indexed as

MechanoreceptorsSensory Receptor CellsAnimalsMiceMuscle, SkeletalMuscle SpindlesProprioceptioncell identityGolgi tendon organmuscle spindleneural developmentproprioceptionsomatosensation

Identifiers

PMID37858440
PMCPMC12743646

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.