Trial reportLipids in health and disease2023
Effect of resistance training and high-intensity interval training on metabolic parameters and serum level of Sirtuin1 in postmenopausal women with metabolic syndrome: a randomized controlled trial.
Trial report in Lipids in health and disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 3 syntheses or guidelines pooled it, 17 citations in OpenAlex.
- Effects of high intensity interval training (HIIT) on cardiopulmonary fitness and physical function in middle-aged and elderly women: a systematic review and meta-analysis.Frontiers in physiology · 2026Pooled it
- Pooled it
- Effects of physical exercise on the lipid profile of perimenopausal and postmenopausal women: a systematic review and meta-analysis.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2025Pooled it
- Effects of 12 weeks of resistance and concurrent training with graded protein intakes on lipid profile, kidney and liver biomarkers in middle-aged to older women.European journal of nutrition · 2026Trial
- Comparative efficacy of various exercise therapies for metabolic syndrome a systematic review and network meta-analysis.iScience · 2026Article
- A Randomized Controlled Trial Comparing High- and Moderate-Intensity Interval Walking on Hematological and Functional Markers in Postmenopausal Women with Obesity.Sports (Basel, Switzerland) · 2026Article
- Review
- Effect of high intensity interval Nordic walking and strength training on selected biomarkers of metabolic syndrome in postmenopausal women with abdominal obesity: a quasi-experimental studies.Frontiers in physiology · 2026Article
- Sirtuins in Women's Health.Pharmaceuticals (Basel, Switzerland) · 2025Review
- From physiology to psychology: An integrative review of menopausal syndrome.World journal of psychiatry · 2025Review
- Effects of 8-Week High-Intensity Interval Training Intervention Regulating the SIRT1/PGC1α Pathway on Hippocampal Neuron Injury and Cognitive Impairment in Obese Rats.Current developments in nutrition · 2025Article
- The effect of different resistance exercise training intensities on cardiovascular risk factors: a systematic review and meta-analysis.European heart journal open · 2025Review
- Impact of Various Kinds of Exercise on Metabolic Parameters in Healthy Post-Menopausal Women: A Systematic Review of Randomized Control Trials.Journal of mid-life healthReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe present study analyzes the influence of resistance training (RT) and high-intensity interval training (HIIT) on metabolic indices and serum levels of Sirtuin1 (SIRT1) in postmenopausal women who suffer from the metabolic syndrome (MetS).
methods45 postmenopausal women aged 45-65 years with MetS were divided into two intervention groups (RT and HIIT) and one control group, each consisting of 15 people. The RT group performed resistance training for both the upper and lower body, while the HIIT group completed 3 min(min) of high-intensity training at 80-90% of their maximum heart rate (HRmax), followed by moderate walking for 3 min at 55-65% of HRmax. These sessions were conducted for a duration of eight weeks and three times a week, with the samples being collected at the baseline and at the end of the treatment, i.e., week 8.
resultsThe results showed that weight, waist circumference, body mass index, fat mass, low-density lipoprotein, triglyceride, cholesterol, fasting blood sugar (FBS), hemoglobin A1c (HbA1C), systolic and diastolic blood pressure decreased, and SIRT1 increased significantly in both training groups. Systolic blood pressure, cholesterol, HbA1C, and FBS decreased more in the HIIT group. Skeletal muscle mass and 1-repetition maximum (1-RM) increased more in the RT group.
conclusionsRT and HIIT serve as one of the most effective strategies for therapeutically treating patients with metabolic syndrome.
trial registrationIRCT, IRCT20221120056548N1. Registered 23 November 2022 - Retrospectively registered.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.