Evidence map›Paper›PMID 37857915›Full record

ReviewOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2024

The influence of iron on bone metabolism disorders.

Hui Zhang, Fan Yang, Zihou Cao, Youjia Xu, Mingyong Wang

Abstract readReview
PubMed Publisher
In one paragraph

Review in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
6.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Targeting CEBPA/ALOX15B attenuates postmenopausal osteoporosis by inhibiting ferroptosis through the AMPK/mTOR signaling pathway.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026
    Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Programmed Cell Death in Rheumatoid Arthritis.Journal of inflammation research · 2025
    Review
  13. Article
  14. Review
  15. Review
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Hui Zhang *Department of Orthopedics, the Second Affiliated Hospital of Soochow University, Suzhou, 215004, China.
Fan Yang *Department of Orthopedics, the Second Affiliated Hospital of Soochow University, Suzhou, 215004, China.
Zihou CaoDepartment of Orthopedics, the Second Affiliated Hospital of Soochow University, Suzhou, 215004, China.
Youjia XuDepartment of Orthopedics, the Second Affiliated Hospital of Soochow University, Suzhou, 215004, China. xuyoujia@suda.edu.cn.
Mingyong WangMurui Biological Technology Co., Ltd, Suzhou Industrial Park, Suzhou, China. maihe123456789@163.com.ORCID http://orcid.org/0000-0002-5705-8145
Soochow University · CNARTS Group (China) · CN

Funding

National Key R&D Program of China 2021YFC2501702
6 · The paper itself

Abstract

Iron is a necessary trace element in the human body, and it participates in many physiological processes. Disorders of iron metabolism can cause lesions in many tissues and organs, including bone. Recently, iron has gained attention as an independent factor influencing bone metabolism disorders, especially the involvement of iron overload in osteoporosis. The aim of this review was to summarize the findings from clinical and animal model research regarding the involvement of iron in bone metabolism disorders and to elucidate the mechanisms behind iron overload and osteoporosis. Lastly, we aimed to describe the association between bone loss and iron overload. We believe that a reduction in iron accumulation can be used as an alternative treatment to assist in the treatment of osteoporosis, to improve bone mass, and to improve the quality of life of patients.

Indexed as

Iron OverloadOsteoporosisAnimalsBone and BonesHumansIronQuality of LifeIronBone metabolismIronOsteoblastOsteoclastReactive oxygen species

Identifiers

PMID37857915
OpenAlexW4387770744

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.