ArticleProstate cancer and prostatic diseases2024
Comparison of perioperative and short-terms outcomes of en-bloc Holmium laser enucleation of the prostate (HoLEP) and robot-assisted simple prostatectomy: a propensity-score matching analysis.
Article in Prostate cancer and prostatic diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07429994 (Predictors of Trifecta Achievement After Holmium Laser Enucleation of the Prostate), which is not on this map. Cited by 17 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Predictors of Trifecta Achievement After Holmium Laser Enucleation of the Prostate
Who cites it
17 citing papers in PubMed, 3 syntheses or guidelines pooled it, 24 citations in OpenAlex.
- Endoscopic enucleation vs. robot-assisted simple prostatectomy for large prostates: a systematic review and meta-analysis of patients' perspectives.Prostate cancer and prostatic diseases · 2026Pooled it
- Robot-assisted simple prostatectomy vs. laser enucleation of the prostate for large-volume benign prostatic hyperplasia (BPH, ≥80 mL): a systematic review and meta-analysis.Frontiers in medicine · 2026Pooled it
- Comparative outcomes of holmium laser enucleation of the prostate (HoLEP) versus robotic-assisted simple prostatectomy (RASP) for benign prostatic hyperplasia: a systematic review and meta-analysis.Journal of robotic surgery · 2025Pooled it
- A randomized controlled trial comparing en-bloc vs lobe-by-lobe HoLEP: surgical efficiency and early continence outcomes.Prostate cancer and prostatic diseases · 2026Trial
- Single-port extraperitoneal robot-assisted simple prostatectomy for benign prostatic hyperplasia: Surgical technique and initial clinical experience.BJUI compass · 2026Article
- Research evolution and clinical positioning of robot-assisted simple prostatectomy for benign prostatic hyperplasia: a bibliometric and visualization analysis.Journal of robotic surgery · 2026Article
- En-bloc and non-en-bloc techniques for thulium laser enucleation of the prostate: a comparative study of surgical outcomes.International urology and nephrology · 2026Article
- Article
- Clinical application of the F21 multipurpose cystoscope with continuous irrigation capability in photoselective vaporization of the prostate: a retrospective controlled study.Frontiers in surgery · 2026Article
- Promising Minimally Invasive Option Emerging in the Treatment of Benign Prostatic Obstruction: Prostatic Artery Embolization.Journal of clinical medicine · 2025Review
- Urethral complications after holmium laser enucleation of the prostate are more common in patients with smaller prostates.Translational andrology and urology · 2025Article
- The Impact of Transurethral Enucleation Therapeutic Approach in All-Size Benign Prostatic Obstruction Pathology: From Contemporary Technological Advances to Evidence-Based Clinical Progresses.Diagnostics (Basel, Switzerland) · 2025Review
- Holmium laser enucleation of the prostate: Learning curve analysis and comparison with TURP.Central European journal of urology · 2025Article
- Comparison of Perioperative Outcomes of Holmium Laser Enucleation of the Prostate for Standard (≤149 ml) Versus Very Large (≥150 ml) Prostate Glands: Retrospective Analysis of a Propensity Score Matched Cohort of 326 Patients.European urology open science · 2025Article
- Evaluation of Peri-Operative Outcomes after Prostatic Urethral Lift with Emphasis on Urodynamic Changes, Symptom Improvement and Sexual Function.Diagnostics (Basel, Switzerland) · 2024Article
- Influence of anterior fibromuscular stroma on incontinence outcomes in RASP and HoLEP: a critical analysis of Grosso et al.'s findings.Prostate cancer and prostatic diseases · 2024Article
- Thulium fiber laser vs. holmium laser enucleation of the prostate: results of a prospective randomized non-inferiority trial.World journal of urology · 2024Article
Corrections and comments
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Authors and funding
15 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSurgical treatment of symptomatic benign prostatic hyperplasia (BPH) has seen an evolution during the last decades. On one hand, en-bloc HoLEP emerged as a valid endoscopic treatment regardless prostate size. On the other hand, robot-assisted simple prostatectomy (RASP) has gained attention in larger prostates showing encouraging results. Herein, for the first time in the scientific scenario, we sought to compare the outcomes of RASP and en-bloc HoLEP cases after propensity-score matching (PSM) analysis.
methodsWe retrospectively queried our prospectively database of patients treated with HoLEP or RASP between 2017 and 2022 among two high-volume centers. PSM was applied based on the International Prostate Symptom Score (IPSS) questionnaire, prostate volume and max-flow rate. All procedures were performed by a single surgeon per center. Outcomes were assessed at 1, 3, and 6-month postoperatively and therefore annually. Trifecta definition was used to assess "success" in surgical procedures and was defined as the contemporary presence of: a) no postoperative complications within the first postoperative month; b) 1-month postoperative Qmax >15 ml/s and c) no urinary incontinence at 3-month evaluation.
resultsOverall, 48 HoLEP and 47 RASPs were matched. Operative time, hospitalization time (median 4 vs 5 days) and catheterization time (median 3 vs 2 day) were found to be shorter in the HoLEP group as compared to the counterpart (p < 0.05). Early postoperative complication rate was also lower in the HoLEP cohort (6.2% vs 12.6%; p = 0.03) as well as postoperative haemoglobine blood level drop (1.4 vs 2.4 g/dL; p = 0.03). On the other hand, postoperative antegrade ejaculation (55.3% vs 6.8%) 1-month max flow (median 28 vs 24 ml/sec) and continence rates (0% vs 20.8%) favored RASP (p < 0.05). Overall, Trifecta rate was similar in the two groups (76.1% vs 82.6%).
conclusionBoth HoLEP and RASP are safe and effective treatments for symptomatic BPH. HoLEP demonstrated to have lower perioperative risks while is affecting by a higher probability of transient early UI. On the other hand, RASP is more effective in reducing postoperative ejaculatory dysfunction.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.