Evidence map›Paper›PMID 37857629›Full record

ArticleBone research2023

Association of mineral and bone biomarkers with adverse cardiovascular outcomes and mortality in the German Chronic Kidney Disease (GCKD) cohort.

Katharina Charlotte Reimer, Jennifer Nadal, Heike Meiselbach, Matthias Schmid, Ulla T Schultheiss, Fruzsina Kotsis, Helena Stockmann, Nele Friedrich, Matthias Nauck, Vera Krane and 6 more

Open access · goldAbstract read
In one paragraph

Article in Bone research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Review
  6. Observational
  7. Review
  8. Review
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 14 institutions in 2 countries.

Katharina Charlotte ReimerDepartment of Nephrology, Rheumatology, and Clinical Immunology, University Hospital RWTH Aachen, Aachen, Germany.
Jennifer NadalInstitute of Medical Biometry, Informatics and Epidemiology, University Hospital of Bonn, Bonn, Germany.
Heike MeiselbachDepartment of Nephrology and Hypertension, University of Erlangen-Nürnberg, Erlangen, Germany.
Matthias SchmidInstitute of Medical Biometry, Informatics and Epidemiology, University Hospital of Bonn, Bonn, Germany.
Ulla T SchultheissInstitute of Genetic Epidemiology, Faculty of Medicine and Medical Center - University of Freiburg, Freiburg, Germany.
Fruzsina KotsisInstitute of Genetic Epidemiology, Faculty of Medicine and Medical Center - University of Freiburg, Freiburg, Germany.
Helena StockmannDepartment of Nephrology and Medical Intensive Care, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Nele FriedrichInstitute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany.
Matthias NauckInstitute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany.ORCID http://orcid.org/0000-0002-6678-7964
Vera KraneDepartment of Medicine I, Division of Nephrology, University Hospital Würzburg, Würzburg, Germany.
Kai-Uwe EckardtDepartment of Nephrology and Hypertension, University of Erlangen-Nürnberg, Erlangen, Germany.
Markus P SchneiderDepartment of Nephrology and Hypertension, University of Erlangen-Nürnberg, Erlangen, Germany.
Rafael KramannDepartment of Nephrology, Rheumatology, and Clinical Immunology, University Hospital RWTH Aachen, Aachen, Germany.
Jürgen FloegeDepartment of Nephrology, Rheumatology, and Clinical Immunology, University Hospital RWTH Aachen, Aachen, Germany.
Turgay SaritasDepartment of Nephrology, Rheumatology, and Clinical Immunology, University Hospital RWTH Aachen, Aachen, Germany. tsaritas@ukaachen.de.ORCID http://orcid.org/0000-0002-6691-9218
GCKD study investigators
Friedrich-Alexander-Universität Erlangen-Nürnberg · DEUniversity of Freiburg · DEInnsbruck Medical University · ATHeidelberg University · DERWTH Aachen University · DECharité - Universitätsmedizin Berlin · DEUniversitätsmedizin Greifswald · DEUniversity Hospital Bonn · DEUniversity of Regensburg · DEUniversity of Würzburg · DEMedizinische Hochschule Hannover · DEUniversitätsklinikum Aachen · DEUniversitätsklinikum Würzburg · DEUniversity Hospital Regensburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mineral and bone disorder (MBD) in chronic kidney disease (CKD) is tightly linked to cardiovascular disease (CVD). In this study, we aimed to compare the prognostic value of nine MBD biomarkers to determine those associated best with adverse cardiovascular (CV) outcomes and mortality. In 5 217 participants of the German CKD (GCKD) study enrolled with an estimated glomerular filtration rate (eGFR) between 30-60 mL·min

Indexed as

Renal Insufficiency, ChronicBiomarkersHumansMineralsParathyroid HormoneVitamin DBiomarkersMineralsParathyroid HormoneVitamin D

Identifiers

PMID37857629
PMCPMC10587182
OpenAlexW4387798584

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.