ArticleNature communications2023
Low mutation rate in epaulette sharks is consistent with a slow rate of evolution in sharks.
Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- Benchmarking genomic variant calling tools in inbred mouse strains: recommendations and considerations.Genetics · 2026Article
- How precise are mutation rate estimates? Comparison of different approaches to estimate de novo mutation rates.Heredity · 2026Article
- Chromosome-level assembly of the Critically Endangered school shark, Galeorhinus galeus (Linnaeus, 1758).Scientific data · 2026Article
- Genome-wide identification and solute selectivity of aquaporins in the sharpnose sevengill shark, Heptranchias perlo.Physiological reports · 2026Article
- First evidence of polyandry for amazonian stingray (Potamotrygon wallacei Carvalho, Rosa & Araújo 2016) based on genome-wide SNP data.Molecular biology reports · 2026Article
- Silver chimaera genome highlights lineage-specific sex chromosome and opsin gene evolution in holocephalans.DNA research : an international journal for rapid publication of reports on genes and genomes · 2026Article
- Stable genome structures in living fossil fishes.Genome research · 2026Article
- Germline de novo mutation rate of the highly heterozygous amphioxus genome.Molecular biology and evolution · 2026Article
- Improved genome assembly of whale shark, the world's biggest fish: revealing intragenomic heterogeneity in molecular evolution.GigaScience · 2026Article
- Evolutionary pathway and genetic mechanisms of fin-to-limb transition in vertebrates.Frontiers in cell and developmental biology · 2026Review
- The ideal candidate for the job: how epaulette sharks (Conservation physiology · 2026Article
- Habitat Availability, Jurassic and Cretaceous Origins of the Deep-Bodied Shark Morphotype and the Rise of Pelagic Sharks.Ecology and evolution · 2025Article
- Sharks and rays have the oldest vertebrate sex chromosome with unique sex determination mechanisms.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Rate of de novo mutations in the three-spined stickleback.Heredity · 2025Article
- The geometry of life: testing the scaling of whole-organism surface area and volume using sharks.Royal Society open science · 2025Article
- Three-dimensional fossils of a Cretaceous collared carpet shark (Parascylliidae, Orectolobiformes) shed light on skeletal evolution in galeomorphs.Royal Society open science · 2025Article
- Decoding deception: the binding affinity of cuttlefish ink on shark smell receptors.G3 (Bethesda, Md.) · 2025Article
- Direct Measurement of the Mutation Rate and Its Evolutionary Consequences in a Critically Endangered Mollusk.Molecular biology and evolution · 2025Article
- The Sensory Shark: High-quality Morphological, Genomic and Transcriptomic Data for the Small-spotted Catshark Scyliorhinus Canicula Reveal the Molecular Bases of Sensory Organ Evolution in Jawed Vertebrates.Molecular biology and evolution · 2024Article
- Comparative genomics illuminates karyotype and sex chromosome evolution of sharks.Cell genomics · 2024Article
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Authors and funding
21 authors.
Funding
Abstract
Sharks occupy diverse ecological niches and play critical roles in marine ecosystems, often acting as apex predators. They are considered a slow-evolving lineage and have been suggested to exhibit exceptionally low cancer rates. These two features could be explained by a low nuclear mutation rate. Here, we provide a direct estimate of the nuclear mutation rate in the epaulette shark (Hemiscyllium ocellatum). We generate a high-quality reference genome, and resequence the whole genomes of parents and nine offspring to detect de novo mutations. Using stringent criteria, we estimate a mutation rate of 7×10
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