Evidence map›Paper›PMID 37857560›Full record

ArticleBMJ open ophthalmology2023

Geographic Atrophy Management Consensus (GA-MAC): a Delphi panel study on identification, diagnosis and treatment.

Peter K Kaiser, Paul M Karpecki, Carl D Regillo, Caroline Baumal, Edwin H Ryan, Michael S Ip, Yasha Modi, Elizabeth Yeu, Lisa Nijm, Marjan Farid and 8 more

Open access · goldAbstract readConsensus Statement
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ open ophthalmology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 13 institutions in 1 country.

Peter K KaiserOphthalmology, Cleveland Clinic Cole Eye Institute, Cleveland, Ohio, USA pkkaiser@gmail.com.ORCID 0000-0001-5126-045X
Paul M KarpeckiOptometry, University of Pikeville, Pikeville, Kentucky, USA.
Carl D RegilloMid Atlantic Retina, Wills Eye Hospital, Philadelphia, Pennsylvania, USA.
Caroline BaumalOphthalmology, New England Eye Center, Boston, Massachusetts, USA.
Edwin H RyanRetina Consultants of Minnesota, VitreoRetinal Surgery, Minneapolis, Minnesota, USA.
Michael S IpOphthalmology, University of California Los Angeles David Geffen School of Medicine, Pasadena, California, USA.
Yasha ModiOphthalmology, New York University, New York, New York, USA.
Elizabeth YeuRefractive Surgery, Virginia Eye Consultants, Norfolk, Virginia, USA.
Lisa NijmOphthalmology and Corneal Surgery, Warrenville Eye Care and LASIK Center, Warrenville, Illinois, USA.
Marjan FaridDepartment of Ophthalmology, University of California Irvine, Irvine, California, USA.
Ronald Luke RebenitschClearSight Lasik, Oklahoma City, Oklahoma, USA.
Terry KimDuke University, Durham, North Carolina, USA.
Diana L ShechtmanEye Centers of South Florida, North Miami Beach, Florida, USA.
Kelly NicholsSchool of Optometry, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Justin SchweitzerOptometry, Vance Thompson Vision, Sioux Falls, South Dakota, USA.
Mark T DunbarBascom Palmer Eye Institute, University of Miami Health System, Miami, Florida, USA.
Mohammad R RafieetaryCharles Retina Institute, Germantown, Tennessee, USA.
Eric D DonnenfeldOCLI VIsion, Cornea, Laser Cataract, and Refractive Surgery, Garden City, New York, USA.
Cleveland Clinic · USDuke University · USEye Centers Of Florida · USNew York University · USRetina Institute · USUniversity of Alabama at Birmingham · USUniversity of California, Irvine · USUniversity of California, Los Angeles · USUniversity of Miami Health System · USUniversity of Pikeville · USVance Thompson Vision · USVirginia Eye Consultants · USWills Eye Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimsWith a paradigm shift in geographic atrophy (GA) treatments now available, establishing consensus on the identification and diagnosis of the disease along with considerations for management of patients with GA will assist eye care professionals (ECP) in their day-to-day practices, leading to improved patient outcomes.

methodsA modified Delphi panel process (Geographic Atrophy Management Consensus) consisting of three total surveys and one virtual live meeting held between survey 2 and survey 3. Data were collected from July to October 2022. Participants included expert members of the eye care community that have demonstrated outstanding leadership among peers: a steering committee with three ECPs and a 15-member panel divided between five optometrists, five comprehensive ophthalmologists and five retina specialists. Consensus on statements related to the management of patients with GA was calculated using the RAND/UCLA Appropriateness Method.

resultsAt the conclusion of the third survey, consensus was reached on 91% of the 77 statements. Critical consensus topics include: (1) optical coherence tomography as the favoured method to diagnose and monitor GA, (2) preferred practice patterns regarding referral of patients to retina specialists and (3) treatment criteria given the advent of emerging therapeutics for GA.

conclusionsGenerating awareness of early signs of disease development, progression and identifying the best tools to evaluate GA establishes ideal management and referral strategies. Given the paradigm shift in GA management driven by approved therapies, coupled with the fact that the disease is progressive resulting in devastating vision loss, these strategies are critical to ensure best overall outcomes.

Indexed as

Geographic AtrophyOptometristsHumansRetinaMaculaRetinaTreatment MedicalVision

Identifiers

PMID37857560
PMCPMC10603481
OpenAlexW4387784582

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.